Results 1 to 10 of about 170,217 (163)

Particle therapy in Europe [PDF]

Molecular Oncology, 2020
Particle therapy using protons or heavier ions is currently the most advanced form of radiotherapy and offers new opportunities for improving cancer care and research. Ions deposit the dose with a sharp maximum – the Bragg peak – and normal tissue receives a much lower dose than what is delivered by X‐ray therapy.
Cai Grau, Marco Durante, Dietmar Georg   +2 more
exaly   +9 more sources

Particle Therapy for Breast Cancer [PDF]

Cancers, 2022
Particle therapy has received increasing attention in the treatment of breast cancer due to its unique physical properties that may enhance patient quality of life and reduce the late effects of therapy. In this review, we will examine the rationale for the use of proton and carbon therapy in the treatment of breast cancer and highlight their potential
Roman O Kowalchuk, Rachel B Jiménez, Corbin Kimberly S   +2 more
exaly   +3 more sources

Evaluation of in vitro irradiation setup: Designed for the horizontal beamline at the Danish Centre for Particle Therapy [PDF]

Acta Oncologica
Background: Radiobiological experimental setups are challenged by precise sample positioning along depth dose profile, scattering conditions, and practical difficulties that must be addressed in individual designs. The aim of this study was to produce
Anders Tobias Frederiksen, Morten Bjørn Jensen, Per Rugaard Poulsen, Niels Bassler, Brita Singers Sørensen, Mateusz Sitarz   +5 more
doaj   +2 more sources

Particle Therapy: Clinical Applications and Biological Effects [PDF]

Life, 2022
Viktoriia Kiseleva, Konstantin Gordon, Polina Vishnyakova   +2 more
exaly   +2 more sources

Particle therapy in the future of precision therapy [PDF]

The British Journal of Radiology, 2020
The first hospital-based treatment facilities for particle therapy started operation about thirty years ago. Since then, the clinical experience with protons and carbon ions has grown continuously and more than 200,000 patients have been treated to date.
Lukas, Schaub, Semi Ben, Harrabi, Juergen, Debus   +2 more
openaire   +2 more sources

Spot-scanning proton therapy for targets with adjacent cardiac implantable electronic devices – Strategies for breast and head & neck cancer

Physics and Imaging in Radiation Oncology, 2022
Background and purpose: Cardiac implantable electronic device (CIED) malfunctions can be induced by secondary neutron dose from spot-scanning proton therapy.
Line Bjerregaard Stick, Peter Magnus Trock Lægdsmand, Henrik Laurits Bjerre, Morten Høyer, Kenneth Jensen, Maria Fuglsang Jensen, Mads Brix Kronborg, Birgitte Vrou Offersen, Camilla Jensenius Skovhus Kronborg   +8 more
doaj   +1 more source

Recent Advances in Metal-Based NanoEnhancers for Particle Therapy [PDF]

Nanomaterials, 2023
Yao-Chen Chuang, Yao-An Shen, Wei-Jun Wang   +2 more
exaly   +2 more sources

Tissue-specific range uncertainty estimation in proton therapy

Physics and Imaging in Radiation Oncology, 2023
Background and Purpose: Proton therapy is sensitive to range uncertainties, which typically are accounted for by margins or robust optimization, based on tissue-independent uncertainties.
Casper Dueholm Vestergaard, Ludvig Paul Muren, Ulrik Vindelev Elstrøm, Jacob Graversen Johansen, Vicki Trier Taasti   +4 more
doaj   +1 more source

Radiobiological model-based approach to determine the potential of dose-escalated robust intensity-modulated proton radiotherapy in reducing gastrointestinal toxicity in the treatment of locally advanced unresectable pancreatic cancer of the head

Radiation Oncology, 2020
Background The purpose of this study was to determine the potential of escalated dose radiation (EDR) robust intensity-modulated proton radiotherapy (ro-IMPT) in reducing GI toxicity risk in locally advanced unresectable pancreatic cancer (LAUPC) of the ...
Vijay P. Raturi, Hidehiro Hojo, Kenji Hotta, Hiromi Baba, Ryo Takahashi, Toshiya Rachi, Naoki Nakamura, Sadamoto Zenda, Atsushi Motegi, Hidenobu Tachibana, Takaki Ariji, Kana Motegi, Masaki Nakamura, Masayuki Okumura, Yasuhiro Hirano, Tetsuo Akimoto   +15 more
doaj   +1 more source

Proton therapy planning and image-guidance strategies within a randomized controlled trial for high-risk prostate cancer

Clinical and Translational Radiation Oncology, 2023
The Danish Prostate Cancer Group is launching the randomized trial, PROstate PROTON Trial 1 (NCT05350475), that compares photons and protons to the prostate and pelvic lymph nodes in treatment of high-risk prostate cancer.
Sofie Tilbæk, Ludvig Paul Muren, Anne Vestergaard, Liliana Stolarczyk, Heidi S. Rønde, Tanja S. Johansen, Jimmi Søndergaard, Morten Høyer, Jan Alsner, Lise Nørgaard Bentzen, Stine Elleberg Petersen   +10 more
doaj   +1 more source