Results 1 to 10 of about 178,392 (266)

Normal tissue complication probability models for prospectively scored late rectal and urinary morbidity after proton therapy of prostate cancer

Physics and Imaging in Radiation Oncology, 2021
Background and purpose: Photons and protons have fundamentally different properties, i.e. protons have a reduced dose bath but a higher relative biological effectiveness. Photon-based normal tissue complication probability (NTCP) models may therefore not
Jesper Pedersen, Xiaoying Liang, Curtis Bryant, Nancy Mendenhall, Zuofeng Li, Ludvig P. Muren   +5 more
doaj   +1 more source

Proton Beam Therapy for Children With Neuroblastoma: Experiences From the Prospective KiProReg Registry

Frontiers in Oncology, 2021
ObjectiveRadiotherapy (RT) is an integral part of the interdisciplinary treatment of patients with high-risk neuroblastoma (NB). With the continuous improvements of outcome, the interest in local treatment strategies that reduce treatment-related side ...
Danny Jazmati, Sarina Butzer, Barbara Hero, Dalia Ahmad Khalil, Julien Merta, Christian Bäumer, Christian Bäumer, Christian Bäumer, Gina Plum, Jörg Fuchs, Friederike Koerber, Theresa Steinmeier, Sarah Peters, Jerome Doyen, Theresa Thole, Matthias Schmidt, Christoph Blase, Stephan Tippelt, Angelika Eggert, Rudolf Schwarz, Thorsten Simon, Beate Timmermann, Beate Timmermann   +22 more
doaj   +1 more source

Treatment plan comparison of proton vs photon radiotherapy for lower-grade gliomas

Physics and Imaging in Radiation Oncology, 2021
Background and purpose: Patients with lower-grade gliomas are long-term survivors after radiotherapy and may benefit from the reduced dose to normal tissue achievable with proton therapy.
Camilla S. Byskov, Christian R. Hansen, Rikke H. Dahlrot, Lene Haldbo-Classen, Charlotte A. Haslund, Flemming Kjær-Kristoffersen, Thomas O. Kristensen, Yasmin Lassen-Ramshad, Slávka Lukacova, Aida Muhic, Petra W. Nyström, Britta Weber, Jesper F. Kallehauge   +12 more
doaj   +1 more source

Circulating cell-free DNA as predictor of pathological complete response in locally advanced rectal cancer patients undergoing preoperative chemoradiotherapy

Clinical and Translational Radiation Oncology, 2022
Background: The watch and wait (W&W) strategy is proposed for patients with locally advanced rectal cancer (LARC) achieving clinical complete response (cCR) after neoadjuvant radiotherapy.
Christina Glismand Truelsen, Camilla Skovhus Kronborg, Brita Singers Sørensen, Louise Bach Callesen, Karen-Lise Garm Spindler   +4 more
doaj   +1 more source

Towards interactive deep-learning for tumour segmentation in head and neck cancer radiotherapy

Physics and Imaging in Radiation Oncology, 2023
Background and purpose: With deep-learning, gross tumour volume (GTV) auto-segmentation has substantially been improved, but still substantial manual corrections are needed. With interactive deep-learning (iDL), manual corrections can be used to update a
Zixiang Wei, Jintao Ren, Stine Sofia Korreman, Jasper Nijkamp   +3 more
doaj   +1 more source

Evaluation of an a priori scatter correction algorithm for cone-beam computed tomography based range and dose calculations in proton therapy

Physics and Imaging in Radiation Oncology, 2020
Background and purpose: Scatter correction of cone-beam computed tomography (CBCT) projections may enable accurate online dose-delivery estimations in photon and proton-based radiotherapy.
Andreas Gravgaard Andersen, Yang-Kyun Park, Ulrik Vindelev Elstrøm, Jørgen Breede Baltzer Petersen, Gregory C. Sharp, Brian Winey, Lei Dong, Ludvig Paul Muren   +7 more
doaj   +1 more source

Comparison of two dual-energy CT-based methods for proton stopping-power ratio estimation in brain cancer patients with metal implants

Acta Oncologica
Background and purpose: Accurate stopping-power ratio (SPR) estimation is crucial for proton therapy planning. In brain cancer patients with metal clips, SPR accuracy may be affected by high-density materials and imaging artefacts.
Ivanka Sojat Tarp, Vicki Trier Taasti, Maria Fuglsang Jensen, Ludvig Paul Muren, Kenneth Jensen   +4 more
doaj   +1 more source

Benefit of range uncertainty reduction in robust optimisation for proton therapy of brain, head-and-neck and breast cancer patients

Physics and Imaging in Radiation Oncology
Background and Purpose: The primary cause of range uncertainty in proton therapy is inaccuracy in estimating the stopping-power ratio from computed tomography.
Ivanka Sojat Tarp, Vicki Trier Taasti, Maria Fuglsang Jensen, Anne Vestergaard, Kenneth Jensen   +4 more
doaj   +1 more source

Is an Endorectal Balloon Beneficial for Rectal Sparing after Spacer Implantation in Prostate Cancer Patients Treated with Hypofractionated Intensity-Modulated Proton Beam Therapy? A Dosimetric and Radiobiological Comparison Study

Current Oncology, 2023
Background: The aim of this study is to examine the dosimetric influence of endorectal balloons (ERB) on rectal sparing in prostate cancer patients with implanted hydrogel rectum spacers treated with dose-escalated or hypofractionated intensity-modulated
Dalia Ahmad Khalil, Jörg Wulff, Danny Jazmati, Dirk Geismar, Christian Bäumer, Paul-Heinz Kramer, Theresa Steinmeier, Stefanie Schulze Schleithoff, Stephan Tschirdewahn, Boris Hadaschik, Beate Timmermann   +10 more
doaj   +1 more source

Proton dose calculation on cone-beam computed tomography using unsupervised 3D deep learning networks

Physics and Imaging in Radiation Oncology
Background and Purpose: Poor image quality of cone-beam computed tomography (CBCT) images can hinder proton dose calculation to assess the influence of anatomy changes.
Casper Dueholm Vestergaard, Ulrik Vindelev Elstrøm, Ludvig Paul Muren, Jintao Ren, Ole Nørrevang, Kenneth Jensen, Vicki Trier Taasti   +6 more
doaj   +1 more source