Results 31 to 40 of about 171,239 (264)

Tumour therapy with particle beams [PDF]

AIP Conference Proceedings, 2000
Photons are exponentially attenuated in matter producing high doses close to the surface. Therefore they are not well suited for the treatment of deep seated tumours. Charged particles, in contrast, exhibit a sharp increase of ionisation density close to the end of their range, the so-called Bragg-peak.
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Air variability in maxillary sinus during radiotherapy for sinonasal carcinoma

Clinical and Translational Radiation Oncology, 2021
Introduction: The aim was to characterise patterns and predictability of aeration changes in the ipsilateral maxillary sinus during intensity-modulated radiotherapy (IMRT) for sinonasal cancer (SNC), and in a sample evaluate the dosimetric effects of ...
M.B. Sharma, R. Argota Perez, A.I.S. Holm, S.S. Korreman, K. Jensen, U.V. Elstrøm, C. Grau   +6 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Beam and spin dynamics in the fast ramping storage ring ELSA: Concepts and measures to increase beam energy, current and polarization

EPJ Web of Conferences, 2017
The electron accelerator facility ELSA has been operated for almost 30 years serving nuclear physics experiments investigating the sub-nuclear structure of matter.
Hillert Wolfgang, Balling Andreas, Boldt Oliver, Dieckmann Andreas, Eberhardt Maren, Frommberger Frank, Heiliger Dominik, Heurich Nikolas, Koop Rebecca, Klarner Fabian, Preisner Oliver, Proft Dennis, Pusch Thorsten, Roth André, Sauerland Dennis, Schedler Manuel, Schmidt Jan Felix, Switka Michael, Thiry Jens-Peter, Wittschen Jürgen, Zander Sven   +20 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Comparing methods to improve cone-beam computed tomography for dose calculations in adaptive proton therapy

Physics and Imaging in Radiation Oncology
Background and purpose: Proton therapy requires dose monitoring, often performed based on repeated computed tomography (reCT) scans. However, reCT scans may not accurately reflect the internal anatomy and patient positioning during treatment.
Casper Dueholm Vestergaard, Nadine Vatterodt, Ulrik Vindelev Elstrøm, Kenneth Jensen, Ole Nørrevang, Ludvig Paul Muren, Stine Sofia Korreman, Vicki Trier Taasti   +7 more
doaj   +1 more source

Risk of second primary cancer from proton arc therapy of pediatric brain tumors

Physics and Imaging in Radiation Oncology, 2023
Proton arc therapy (PAT) is currently explored for clinical implementation, despite its associated low-dose bath. This study therefore aimed at evaluating the risk of radiation-induced second primary cancer (SPC) for PAT in pediatric brain tumor patients.
Laura Toussaint, Daniel J Indelicato, Ludvig P Muren, Camilla H Stokkevåg   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three-year insights from a proton therapy centre: Evolving strategies in ependymoma treatment planning

Technical Innovations & Patient Support in Radiation Oncology
Background: Treatment of posterior fossa ependymoma with proton therapy (PT) is challenging due to the proximity to the brainstem and potential risk of brainstem toxicity.
Lieselotte Lauwens, Anneleen Goedgebeur, Tom Boterberg, Tom Depuydt, Dario Di Perri, Lorraine Donnay, Benjamin Ledoux, Kenneth Poels, Susana Santos Lopes, Karen Van Beek, Robin De Roover, Maarten Lambrecht   +11 more
doaj   +1 more source