Results 21 to 30 of about 171,239 (264)

Evaluation of an a priori scatter correction algorithm for cone-beam computed tomography based range and dose calculations in proton therapy

Physics and Imaging in Radiation Oncology, 2020
Background and purpose: Scatter correction of cone-beam computed tomography (CBCT) projections may enable accurate online dose-delivery estimations in photon and proton-based radiotherapy.
Andreas Gravgaard Andersen, Yang-Kyun Park, Ulrik Vindelev Elstrøm, Jørgen Breede Baltzer Petersen, Gregory C. Sharp, Brian Winey, Lei Dong, Ludvig Paul Muren   +7 more
doaj   +1 more source

Particle therapy for noncancer diseases [PDF]

Medical Physics, 2012
Radiation therapy using high‐energy charged particles is generally acknowledged as a powerful new technique in cancer treatment. However, particle therapy in oncology is still controversial, specifically because it is unclear whether the putative clinical advantages justify the high additional costs.
C. Bert, R. Engenhart Cabillic, DURANTE, MARCO   +2 more
openaire   +3 more sources

Comparison of two dual-energy CT-based methods for proton stopping-power ratio estimation in brain cancer patients with metal implants

Acta Oncologica
Background and purpose: Accurate stopping-power ratio (SPR) estimation is crucial for proton therapy planning. In brain cancer patients with metal clips, SPR accuracy may be affected by high-density materials and imaging artefacts.
Ivanka Sojat Tarp, Vicki Trier Taasti, Maria Fuglsang Jensen, Ludvig Paul Muren, Kenneth Jensen   +4 more
doaj   +1 more source

Benefit of range uncertainty reduction in robust optimisation for proton therapy of brain, head-and-neck and breast cancer patients

Physics and Imaging in Radiation Oncology
Background and Purpose: The primary cause of range uncertainty in proton therapy is inaccuracy in estimating the stopping-power ratio from computed tomography.
Ivanka Sojat Tarp, Vicki Trier Taasti, Maria Fuglsang Jensen, Anne Vestergaard, Kenneth Jensen   +4 more
doaj   +1 more source

Is an Endorectal Balloon Beneficial for Rectal Sparing after Spacer Implantation in Prostate Cancer Patients Treated with Hypofractionated Intensity-Modulated Proton Beam Therapy? A Dosimetric and Radiobiological Comparison Study

Current Oncology, 2023
Background: The aim of this study is to examine the dosimetric influence of endorectal balloons (ERB) on rectal sparing in prostate cancer patients with implanted hydrogel rectum spacers treated with dose-escalated or hypofractionated intensity-modulated
Dalia Ahmad Khalil, Jörg Wulff, Danny Jazmati, Dirk Geismar, Christian Bäumer, Paul-Heinz Kramer, Theresa Steinmeier, Stefanie Schulze Schleithoff, Stephan Tschirdewahn, Boris Hadaschik, Beate Timmermann   +10 more
doaj   +1 more source

Proton dose calculation on cone-beam computed tomography using unsupervised 3D deep learning networks

Physics and Imaging in Radiation Oncology
Background and Purpose: Poor image quality of cone-beam computed tomography (CBCT) images can hinder proton dose calculation to assess the influence of anatomy changes.
Casper Dueholm Vestergaard, Ulrik Vindelev Elstrøm, Ludvig Paul Muren, Jintao Ren, Ole Nørrevang, Kenneth Jensen, Vicki Trier Taasti   +6 more
doaj   +1 more source

Hadron particle therapy

Proceedings Particle Accelerator Conference, 2002
Hadron therapy is a maturing field, with strengths and weaknesses that have been clearly identified. For certain tumour types, particles have become the treatment of choice, and hospital-based implementation of these techniques are coming on line. Focused RD effective control requires a wide arsenal of treatment techniques.
openaire   +2 more sources

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Empirical quenching correction in radiochromic silicone-based three-dimensional dosimetry of spot-scanning proton therapy

Physics and Imaging in Radiation Oncology, 2021
Background and purpose: Three-dimensional dosimetry of proton therapy (PT) with chemical dosimeters is challenged by signal quenching, which is a lower dose-response in regions with high ionization density due to high linear-energy-transfer (LET) and ...
Lia Barbosa Valdetaro, Ellen Marie Høye, Peter Sandegaard Skyt, Jørgen Breede Baltzer Petersen, Peter Balling, Ludvig Paul Muren   +5 more
doaj   +1 more source