Results 11 to 20 of about 182,390 (296)

Particle therapy for noncancer diseases [PDF]

Medical Physics, 2012
Radiation therapy using high‐energy charged particles is generally acknowledged as a powerful new technique in cancer treatment. However, particle therapy in oncology is still controversial, specifically because it is unclear whether the putative clinical advantages justify the high additional costs.
C. Bert, R. Engenhart Cabillic, DURANTE, MARCO   +2 more
openaire   +4 more sources

Particle therapy masterclass [PDF]

EPJ Web of Conferences, 2022
The aim of the new Particle Therapy MasterClass (PTMC) was to develop an educational and training environment in which anyone can learn about fundamental and applied research in particle therapy. The PTMC was recently integrated into the International MasterClass 2021 online programme that attracted 1500 students from 37 institutes in 20 countries ...
Foka Panagiota, Mamaras Aristeidis, Skrjiel Damir, Seco Joao, Graeff Christian, Pulia Marco, Wieser Hans-Peter, Wahl Niklas   +7 more
core   +5 more sources

Intrafraction tumor motion monitoring and dose reconstruction for liver pencil beam scanning proton therapy

Frontiers in Oncology, 2023
BackgroundPencil beam scanning (PBS) proton therapy can provide highly conformal target dose distributions and healthy tissue sparing. However, proton therapy of hepatocellular carcinoma (HCC) is prone to dosimetrical uncertainties induced by respiratory
Saber Nankali, Saber Nankali, Esben Schjødt Worm, Jakob Borup Thomsen, Line Bjerregaard Stick, Jenny Bertholet, Morten Høyer, Britta Weber, Britta Weber, Hanna Rahbek Mortensen, Per Rugaard Poulsen, Per Rugaard Poulsen   +11 more
doaj   +1 more source

Dose–Volume and Radiobiological Model-Based Comparative Evaluation of the Gastrointestinal Toxicity Risk of Photon and Proton Irradiation Plans in Localized Pancreatic Cancer Without Distant Metastasis

Frontiers in Oncology, 2020
Background: Radiobiological model-based studies of photon-modulated radiotherapy for pancreatic cancer have reported reduced gastrointestinal (GI) toxicity, although the risk is still high. The purpose of this study was to investigate the potential of 3D-
Vijay P. Raturi, Vijay P. Raturi, Taku Tochinai, Hidehiro Hojo, Toshiya Rachi, Kenji Hotta, Naoki Nakamura, Sadamoto Zenda, Atsushi Motegi, Takaki Ariji, Yasuhiro Hirano, Hiromi Baba, Hajime Ohyoshi, Masaki Nakamura, Masayuki Okumura, Yanping Bei, Tetsuo Akimoto, Tetsuo Akimoto   +17 more
doaj   +1 more source

Dose-response of deformable radiochromic dosimeters for spot scanning proton therapy

Physics and Imaging in Radiation Oncology, 2020
Intrafractional motion and deformation influence proton therapy delivery for tumours in the thorax, abdomen and pelvis. This study aimed to test the dose–response of a compressively strained three-dimensional silicone-based radiochromic dosimeter during ...
Simon V. Jensen, Lia B. Valdetaro, Per R. Poulsen, Peter Balling, Jørgen B.B. Petersen, Ludvig P. Muren   +5 more
doaj   +1 more source

Dosimetric feasibility of moderately hypofractionated/dose escalated radiation therapy for localised prostate cancer with intensity-modulated proton beam therapy using simultaneous integrated boost (SIB-IMPT) and impact of hydrogel prostate-rectum spacer

Radiation Oncology, 2022
Purpose To examine the dosimetric feasibility of hypofractionated/dose escalated radiation therapy in patients with localized prostate carcinoma using simultaneous integrated boost intensity-modulated proton beam therapy (SIB-IMPT) in absence or presence
Dalia Ahmad Khalil, Danny Jazmati, Dirk Geismar, Jörg Wulff, Christian Bäumer, Paul Heinz Kramer, Theresa Steinmeier, Stefanie Schulze Schleitthoff, Sandija Plaude, Martin Bischoff, Stephan Tschirdewahn, Boris Hadaschik, Beate Timmermann   +12 more
doaj   +1 more source

Molecular Signaling in Response to Charged Particle Exposures and its Importance in Particle Therapy [PDF]

, 2018
Energetic, charged particles elicit an orchestrated DNA damage response (DDR) during their traversal through healthy tissues and tumors. Complex DNA damage formation, after exposure to high linear energy transfer (LET) charged particles, results in ...
Hellweg, Christine E., Chishti, Arif Ali, Diegeler, Sebastian, Baumstark-Khan, Christa, Henschenmacher, Bernd, Spitta, Luis F.   +5 more
core   +1 more source

Dosimetric comparison between proton beam therapy and photon radiation therapy for locally advanced esophageal squamous cell carcinoma

Radiation Oncology, 2018
Background The purpose of this study was to perform a dosimetric comparison between proton beam therapy (PBT) and photon radiation therapy in patients with locally advanced esophageal squamous cell carcinoma (ESCC) who were treated with PBT in our ...
Yasuhiro Hirano, Masakatsu Onozawa, Hidehiro Hojo, Atsushi Motegi, Sadatomo Zenda, Kenji Hotta, Shunsuke Moriya, Hidenobu Tachibana, Naoki Nakamura, Takashi Kojima, Tetsuo Akimoto   +10 more
doaj   +1 more source

Normal tissue complication probability models for prospectively scored late rectal and urinary morbidity after proton therapy of prostate cancer

Physics and Imaging in Radiation Oncology, 2021
Background and purpose: Photons and protons have fundamentally different properties, i.e. protons have a reduced dose bath but a higher relative biological effectiveness. Photon-based normal tissue complication probability (NTCP) models may therefore not
Jesper Pedersen, Xiaoying Liang, Curtis Bryant, Nancy Mendenhall, Zuofeng Li, Ludvig P. Muren   +5 more
doaj   +1 more source

Proton Beam Therapy for Children With Neuroblastoma: Experiences From the Prospective KiProReg Registry

Frontiers in Oncology, 2021
ObjectiveRadiotherapy (RT) is an integral part of the interdisciplinary treatment of patients with high-risk neuroblastoma (NB). With the continuous improvements of outcome, the interest in local treatment strategies that reduce treatment-related side ...
Danny Jazmati, Sarina Butzer, Barbara Hero, Dalia Ahmad Khalil, Julien Merta, Christian Bäumer, Christian Bäumer, Christian Bäumer, Gina Plum, Jörg Fuchs, Friederike Koerber, Theresa Steinmeier, Sarah Peters, Jerome Doyen, Theresa Thole, Matthias Schmidt, Christoph Blase, Stephan Tippelt, Angelika Eggert, Rudolf Schwarz, Thorsten Simon, Beate Timmermann, Beate Timmermann   +22 more
doaj   +1 more source