Results 41 to 50 of about 182,390 (296)

Air variability in maxillary sinus during radiotherapy for sinonasal carcinoma

Clinical and Translational Radiation Oncology, 2021
Introduction: The aim was to characterise patterns and predictability of aeration changes in the ipsilateral maxillary sinus during intensity-modulated radiotherapy (IMRT) for sinonasal cancer (SNC), and in a sample evaluate the dosimetric effects of ...
M.B. Sharma, R. Argota Perez, A.I.S. Holm, S.S. Korreman, K. Jensen, U.V. Elstrøm, C. Grau   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Beam and spin dynamics in the fast ramping storage ring ELSA: Concepts and measures to increase beam energy, current and polarization

EPJ Web of Conferences, 2017
The electron accelerator facility ELSA has been operated for almost 30 years serving nuclear physics experiments investigating the sub-nuclear structure of matter.
Hillert Wolfgang, Balling Andreas, Boldt Oliver, Dieckmann Andreas, Eberhardt Maren, Frommberger Frank, Heiliger Dominik, Heurich Nikolas, Koop Rebecca, Klarner Fabian, Preisner Oliver, Proft Dennis, Pusch Thorsten, Roth André, Sauerland Dennis, Schedler Manuel, Schmidt Jan Felix, Switka Michael, Thiry Jens-Peter, Wittschen Jürgen, Zander Sven   +20 more
doaj   +1 more source

Hadron particle therapy

Proceedings Particle Accelerator Conference, 2002
Hadron therapy is a maturing field, with strengths and weaknesses that have been clearly identified. For certain tumour types, particles have become the treatment of choice, and hospital-based implementation of these techniques are coming on line. Focused RD effective control requires a wide arsenal of treatment techniques.
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Risk of second primary cancer from proton arc therapy of pediatric brain tumors

Physics and Imaging in Radiation Oncology, 2023
Proton arc therapy (PAT) is currently explored for clinical implementation, despite its associated low-dose bath. This study therefore aimed at evaluating the risk of radiation-induced second primary cancer (SPC) for PAT in pediatric brain tumor patients.
Laura Toussaint, Daniel J Indelicato, Ludvig P Muren, Camilla H Stokkevåg   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Comparing methods to improve cone-beam computed tomography for dose calculations in adaptive proton therapy

Physics and Imaging in Radiation Oncology
Background and purpose: Proton therapy requires dose monitoring, often performed based on repeated computed tomography (reCT) scans. However, reCT scans may not accurately reflect the internal anatomy and patient positioning during treatment.
Casper Dueholm Vestergaard, Nadine Vatterodt, Ulrik Vindelev Elstrøm, Kenneth Jensen, Ole Nørrevang, Ludvig Paul Muren, Stine Sofia Korreman, Vicki Trier Taasti   +7 more
doaj   +1 more source

Lissajous trajectory magnetic particle imaging for image-guided hyperthermia therapy and monitoring

, 2022
Magnetic field hyperthermia (MFH) therapy is an emerging cancer treatment which uses heat to damage tumors. Like magnetic particle imaging (MPI), MFH combines injected magnetic nanoparticles with the subsequent application of time-varying magnetic fields.
Twamley, Shailey, Wells, James, Paysen, Hendrik, Kosch, Olaf, Ludwig, Antje, Wiekhorst, Frank, Paeye, Joran   +6 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source