Concepts of microdosimetry [PDF]
Radiation and Environmental Biophysics, 1975 This is the first part of an investigation of microdosimetric concepts relevant to numerical calculations. The definitions of the microdosimetric quantities are reviewed and formalized, and some additional conventions are adopted. The common interpretation of the quantities in terms of energy imparted to spherical sites is contrasted with their ...
A M, Kellerer, D, Chmelevsky
core +8 more sources
Current Radiopharmaceuticalse, 2011 With the increasing availability of alpha emitters, targeted α-particle therapy has emerged as a solution of choice to treat haematological cancers and micrometastatic and minimal residual diseases. Alpha-particles are highly cytotoxic because of their high linear energy transfer (LET) and have a short range of a few cell diameters in tissue, assuring ...
Nicolas, Chouin, Manuel, Bardies
openaire +3 more sources
Boron Neutron Capture Therapy: Microdosimetry at Different Boron Concentrations
Applied Sciences, 2023 This paper explores the role of microdosimetry in boron neutron capture therapy (BNCT), a cancer treatment involving the selective accumulation of boron-containing compounds in cancer cells, followed by neutron irradiation.
Valeria Conte, Anna Bianchi, Anna Selva
doaj +2 more sources
Targeted Radionuclide Therapy:How to correlate microdosimetry with biological effects [PDF]
, 2022 The aim of this work is to improve the current computational dosimetry approaches for in vitro and in vivo TRT treatment in order to correlate microdosimetry with biological effects.
Tamborino, Giulia
core +9 more sources
An analytical framework for efficient and precision-controlled Monte Carlo simulation of heterogeneous targeted alpha therapy microdosimetry. [PDF]
Med PhysBackground Dosimetric studies of targeted alpha therapy (TAT) show that microscopic heterogeneity in geometry and source distribution strongly affects dose‐effect relationships, underscoring the potential of microdosimetry.
Zhu J, Cao S, Li X, Qi Y, Chen Z.
europepmc +2 more sources
Towards standardization in microdosimetry: Addressing stochastic and non‐stochastic radiation interactions [PDF]
Precis Radiat OncolPrecision Radiation Oncology, EarlyView.
Magrin G.
europepmc +2 more sources
Fast microdosimetry algorithms in particle therapy: Benchmark and applicability guidelines [PDF]
Precis Radiat OncolPrecision Radiation Oncology, EarlyView.
Cartechini G, Missiaggia M, Cordoni F.
europepmc +2 more sources
Experimental and computational characterisation of the secondary fragment field in clinical proton therapy beams using microdosimetry [PDF]
Precis Radiat OncolPrecision Radiation Oncology, EarlyView.
Parisi G +7 more
europepmc +2 more sources
A novel system for micron-scale analysis of energy deposition and response to low-dose radiation. [PDF]
Med PhysAbstract Background Micrometer‐scale evaluation of energy deposition is important for radiation protection and therapy as well as for advancing knowledge of responses to radiation in materials and biological systems. Due to the stochastic nature of radiation interactions, there is significant variation in energy deposition in micrometer‐sized targets ...
Pasricha P +11 more
europepmc +2 more sources
A mechanistic‐based normal tissue complication probability (NTCP) prediction through a microdosimetry‐based multiscale radiation biophysical model (MS‐GSM2) [PDF]
Precis Radiat OncolPrecision Radiation Oncology, EarlyView.
Battestini M +5 more
europepmc +2 more sources