Results 31 to 40 of about 3,468 (205)

Microdosimetric Investigation and a Novel Model of Radiosensitization in the Presence of Metallic Nanoparticles

Pharmaceutics, 2021
Auger cascades generated in high atomic number nanoparticles (NPs) following ionization were considered a potential mechanism for NP radiosensitization. In this work, we investigated the microdosimetric consequences of the Auger cascades using the theory
Huagang Yan, David J. Carlson, Ramin Abolfath, Wu Liu   +3 more
doaj   +1 more source

A Model for Estimating Dose-Rate Effects on Cell-Killing of Human Melanoma after Boron Neutron Capture Therapy

Cells, 2020
Boron neutron capture therapy (BNCT) is a type of radiation therapy for eradicating tumor cells through a 10B(n,α)7Li reaction in the presence of 10B in cancer cells.
Yusuke Matsuya, Hisanori Fukunaga, Motoko Omura, Hiroyuki Date   +3 more
doaj   +1 more source

Simultaneous Measurements of Dose and Microdosimetric Spectra in a Clinical Proton Beam Using a scCVD Diamond Membrane Microdosimeter

Sensors, 2021
A single crystal chemical vapor deposition (scCVD) diamond membrane-based microdosimetric system was used to perform simultaneous measurements of dose profile and microdosimetric spectra with the Y1 proton passive scattering beamline of the Center of ...
Oluwasayo Loto, Izabella Zahradnik, Amelia Maia Leite, Ludovic De Marzi, Dominique Tromson, Michal Pomorski   +5 more
doaj   +1 more source

Linking Microdosimetric Measurements to Biological Effectiveness in Ion Beam Therapy: A Review of Theoretical Aspects of MKM and Other Models

Frontiers in Physics, 2021
Different qualities of radiation are known to cause different biological effects at the same absorbed dose. Enhancements of the biological effectiveness are a direct consequence of the energy deposition clustering at the scales of DNA molecule and cell ...
V. E. Bellinzona, V. E. Bellinzona, F. Cordoni, F. Cordoni, M. Missiaggia, M. Missiaggia, F. Tommasino, F. Tommasino, E. Scifoni, C. La Tessa, C. La Tessa, A. Attili   +11 more
doaj   +1 more source

Technological and theoretical aspects for testing electroporation on liposomes [PDF]

, 2017
Recently, the use of nanometer liposomes as nanocarriers in drug delivery systems mediated by nanoelectroporation has been proposed. This technique takes advantage of the possibility of simultaneously electroporating liposomes and cell membrane with 10 ...
Apollonio, Francesca, Denzi, Agnese, Esposito, Gianluca, Liberti, Micaela, Mir, Lluis M., Valle, Elena Della   +5 more
core   +3 more sources

Clonogenic Survival RBE Calculations in Carbon Ion Therapy: The Importance of the Absolute Values of α and β in the Photon Dose-Response Curve and a Strategy to Mitigate Their Anticorrelation

Quantum Beam Science, 2023
The computation of the relative biological effectiveness (RBE) is a fundamental step in the planning of cancer radiotherapy treatments with accelerated ions.
Alessio Parisi, Chris J. Beltran, Keith M. Furutani   +2 more
doaj   +1 more source

Microdosimetry

Istituto Lombardo - Accademia di Scienze e Lettere - Rendiconti di Scienze, 2023
The interest in the application of microdosimetry for assessing the radiation quality of hadrontherapy fields has grown in the last two decades. The reference detector for microdosimetry is the tissue-equivalent proportional counter (TEPC). Novel types of microdosimeters have been developed by the Nuclear Measurement Laboratory of the Politecnico di ...
openaire   +2 more sources

Energy-Loss Straggling and Delta-Ray Escape in Solid-State Microdosimeters Used in Ion-Beam Therapy

Journal of Nuclear Engineering, 2022
Microdosimetry is increasingly adopted in the characterization of proton and carbon ion beams used in cancer therapy. Spectra and mean values of lineal energy calculated in frequency and dose are seen by many as the tools which, by complementing ...
Giulio Magrin, Sandra Barna, Cynthia Meouchi, Anatoly Rosenfeld, Hugo Palmans   +4 more
doaj   +1 more source

Parameters of track structure [PDF]

, 1970
Linear energy transfer (or collision stopping power) and energy straggling along the tracks of charged particles are both relevant to the effectiveness of ionizing radiation.
Kellerer, Albrecht M.
core   +1 more source

Preparation of tissue equivalent conductive polyamide/polyethylene nanocomposite containing carbon nanotubes as electrode of the gaseous microdosimeters [PDF]

مجله علوم و فنون هسته‌ای, 2019
The aim of this study is preparing a conductive tissue equivalent composite similar to expensive and limited access commercial A-150 plastic, in which, the Conductive Carbon Nanotubes (CNT) are used instead of black carbon.
F Khoylou, A Akhavan, F Naimian, A Moslehi   +3 more
doaj   +1 more source