Results 31 to 40 of about 1,709 (213)

A Novel Hybrid Microdosimeter for Radiation Field Characterization Based on the Tissue Equivalent Proportional Counter Detector and Low Gain Avalanche Detectors Tracker: A Feasibility Study

Frontiers in Physics, 2021
In microdosimetry, lineal energies y are calculated from energy depositions ϵ inside the microdosimeter divided by the mean chord length, whose value is based on geometrical assumptions on both the detector and the radiation field.
M. Missiaggia, M. Missiaggia, M. Missiaggia, E. Pierobon, M. Castelluzzo, A. Perinelli, F. Cordoni, F. Cordoni, M. Centis Vignali, G. Borghi, G. Borghi, E. V. Bellinzona, E. V. Bellinzona, E. Scifoni, F. Tommasino, F. Tommasino, V. Monaco, L. Ricci, L. Ricci, M. Boscardin, M. Boscardin, Chiara La Tessa, Chiara La Tessa   +22 more
doaj   +1 more source

Silicon 3D Microdosimeters for Advanced Quality Assurance in Particle Therapy

Applied Sciences, 2021
The Centre for Medical Radiation Physics introduced the concept of Silicon On Insulator (SOI) microdosimeters with 3-Dimensional (3D) cylindrical sensitive volumes (SVs) mimicking the dimensions of cells in an array. Several designs of high-definition 3D
Linh T. Tran, David Bolst, Benjamin James, Vladimir Pan, James Vohradsky, Stefania Peracchi, Lachlan Chartier, Emily Debrot, Susana Guatelli, Marco Petasecca, Michael Lerch, Dale Prokopovich, Željko Pastuović, Marco Povoli, Angela Kok, Taku Inaniwa, Sung Hyun Lee, Naruhiro Matsufuji, Anatoly B. Rosenfeld   +18 more
doaj   +1 more source

Lineal Energy of Proton in Silicon by a Microdosimetry Simulation

Applied Sciences, 2021
Single event upset, or Single Event Effect (SEE) is increasingly important as semiconductor devices are entering into nano-meter scale. The Linear Energy Transfer (LET) concept is commonly used to estimate the rate of SEE.
Yueh Chiang, Cher Ming Tan, Chuan-Jong Tung, Chung-Chi Lee, Tsi-Chian Chao   +4 more
doaj   +1 more source

Bridging Microdosimetry and Macrodosimetry: A Comparative Review of Computational Approaches [PDF]

Journal of Radiation Protection and Research
Microdosimetry does not simply refer to dosimetry with small targets, but rather to dosimetry that accounts for the stochastic nature of energy deposition.
Tatsuhiko Sato
doaj   +1 more source

Predicting the Biological Effects of Human Salivary Gland Tumour Cells for Scanned ⁴He-, ¹²C-, ¹⁶O-, and ²⁰Ne-Ion Beams Using an SOI Microdosimeter

Applied Sciences, 2022
Experimental microdosimetry along with the microdosimetric kinetic (MK) model can be utilized to predict the biological effects of ions. To predict the relative biological effectiveness (RBE) of ions and the survival fraction (SF) of human salivary gland
Sung Hyun Lee, Kota Mizushima, Shunsuke Yonai, Shinnosuke Matsumoto, Hideyuki Mizuno, Taku Nakaji, Ryosuke Kohno, Yoshiyuki Iwata, Toshiyuki Shirai, Vladimir Pan, Angela Kok, Marco Povoli, Linh T. Tran, Anatoly B. Rosenfeld, Masao Suzuki, Taku Inaniwa   +15 more
doaj   +1 more source

Impact of Radiation Quality on Microdosimetry and Chromosome Aberrations for High-Energy (>250 MeV/n) Ions

Life, 2022
Studying energy deposition by space radiation at the cellular scale provides insights on health risks to astronauts. Using the Monte Carlo track structure code RITRACKS, and the chromosome aberrations code RITCARD, we performed a modeling study of single-
Floriane Poignant, Ianik Plante, Luis Crespo, Tony Slaba   +3 more
doaj   +1 more source

Microdosimetric Investigation and a Novel Model of Radiosensitization in the Presence of Metallic Nanoparticles

Pharmaceutics, 2021
Auger cascades generated in high atomic number nanoparticles (NPs) following ionization were considered a potential mechanism for NP radiosensitization. In this work, we investigated the microdosimetric consequences of the Auger cascades using the theory
Huagang Yan, David J. Carlson, Ramin Abolfath, Wu Liu   +3 more
doaj   +1 more source

Microdosimetry of diagnostic X-rays: applications of the variance-covariance method. [PDF]

, 1992
Microdosimetric measurements in beams of diagnostic X rays (between 30 and 125 kV) have been performed. In these pulsed radiation fields, microdosimetric measurements are possible only by application of the variance-covariance technique.
Kellerer, Albrecht M., Chen, J., Kellerer, A.M., Roos, H.   +3 more
core   +1 more source

Internal microdosimetry of alpha-emitting radionuclides. [PDF]

, 2020
At the tissue level, energy deposition in cells is determined by the microdistribution of alpha-emitting radionuclides in relation to sensitive target cells.
Friedland, W., Madas, Balázs, Bardiès, Manuel, Madas, B., Miller, B.W., Li, Wei Bo, Bardies, M., Hofmann, Werner, Miller, Brian W., Balashazy, I., Balásházy, Imre, Hofmann, W., Li, W.B., Friedland, Werner   +13 more
core   +1 more source

A Model for Estimating Dose-Rate Effects on Cell-Killing of Human Melanoma after Boron Neutron Capture Therapy

Cells, 2020
Boron neutron capture therapy (BNCT) is a type of radiation therapy for eradicating tumor cells through a 10B(n,α)7Li reaction in the presence of 10B in cancer cells.
Yusuke Matsuya, Hisanori Fukunaga, Motoko Omura, Hiroyuki Date   +3 more
doaj   +1 more source