RBE, Reference RBE and Clinical RBE: Applications of These Concepts in Hadron Therapy
Introduction of heavy particles (hadrons) into radiation therapy aims at improving the physical selectivity of the irradiation (e.g. proton beams), or the radiobiological differential effect (e.g. fast neutrons), or both (e.g. heavy-ion beams). Each of these new therapy modalities requires several types of information before prescribing safely the ...
A Wambersie, André Wambersie
exaly +4 more sources
A standardized measurement-based approach to estimate modelled relative biological effectiveness for auditing carbon ion beams [PDF]
Background and purpose: Differences in dose delivered during carbon radiotherapy are due largely to variations in relative biological effectiveness (RBE), which can be calculated by several models.
Shannon Hartzell +8 more
doaj +2 more sources
Microdosimetric characterization of proton relative biological effectiveness in pancreatic ductal adenocarcinoma cell lines [PDF]
PurposePancreatic ductal adenocarcinoma (PDAC) is among the most radioresistant malignancies. Proton therapy assumes a uniform relative biological effectiveness (RBE) of 1.1 regardless of radiation quality.
Tianyu Wang +9 more
doaj +2 more sources
Deviations from the inverse relationship between tumor and normal tissue dose and RBE in fast neutron data are compatible with the presence of hypoxia, with possible applications to hypo-fractionated proton therapy [PDF]
Aim of studyFast neutron data from Hammersmith (UK) showed that the inverse relationship between dose and RBE (Relative Biological Effectiveness) is not maintained in many in vivo situations, originally attributed to hypoxic effects.
Bleddyn Jones, Bleddyn Jones
doaj +2 more sources
Who labels best? Radiologists, rules, or large language models for CT reports on pulmonary embolism [PDF]
Objective To compare open-weight and proprietary large language models (LLMs), a rule-based extractor (RBE) and radiologists for labelling pulmonary embolism CT reports, and to test whether a hybrid RBE–LLM workflow improves labelling performance ...
Matthias A. Fink +10 more
doaj +2 more sources
THE ROLE AND PLACE OF SELF-MANAGEMENT IN THE LABOR MANAGEMENT SYSTEM OF SPECIALISTS OF ROAD AND BRIDGE ENTERPRISES [PDF]
The objective of the study consists in determining the essence and features of self-management in the labor management system of specialists of road and bridge enterprises (RBE) and its role and place in the specified system.
Artem Bezuglyi, Viktor Komar
doaj +1 more source
Genomic Diversity of the Ostreid Herpesvirus Type 1 Across Time and Location and Among Host Species
The mechanisms underlying virus emergence are rarely well understood, making the appearance of outbreaks largely unpredictable. This is particularly true for pathogens with low per-site mutation rates, such as DNA viruses, that do not exhibit a large ...
Benjamin Morga +14 more
doaj +1 more source
A Comprehensive Review for the Surveillance of Human Pathogenic Microorganisms in Shellfish
Bivalve molluscan shellfish have been consumed for centuries. Being filter feeders, they may bioaccumulate some microorganisms present in coastal water, either naturally or through the discharge of human or animal sewage.
Marion Desdouits +3 more
doaj +1 more source
Fecal pollution in coastal areas is of a high concern since it affects bathing and shellfish harvesting activities. Wild waterbirds are non-negligible in the overall signal of the detectable pollution.
Amine M. Boukerb +8 more
doaj +1 more source

