Results 51 to 60 of about 2,193 (191)

Characterizing Radiation Effectiveness in Ion Beam Therapy Part I: Introduction and Biophysical Modeling of RBE Using the LEMIV

Frontiers in Physics, 2020
The specific advantages of ion beams for application in tumor therapy are attributed to their different macroscopic and microscopic energy deposition pattern as compared to conventional photon radiation.
Michael Scholz, Thomas Friedrich, Giulio Magrin, Paolo Colautti, Aleksandra Ristić-Fira, Ivan Petrović   +5 more
doaj   +1 more source

Microdosimetric Investigation and a Novel Model of Radiosensitization in the Presence of Metallic Nanoparticles

Pharmaceutics, 2021
Auger cascades generated in high atomic number nanoparticles (NPs) following ionization were considered a potential mechanism for NP radiosensitization. In this work, we investigated the microdosimetric consequences of the Auger cascades using the theory
Huagang Yan, David J. Carlson, Ramin Abolfath, Wu Liu   +3 more
doaj   +1 more source

Low intensity configuration at NTF for microdosimetry and spectroscopy [PDF]

, 1995
Additional circuitry has been developed to regulate beam delivery to Fermilab`s Neutron Therapy Facility. This allows the number of protons on target to be reduced to a point that makes microdosimetry and spectroscopy possible.
Kroc, T.K.
core   +1 more source

Simultaneous Measurements of Dose and Microdosimetric Spectra in a Clinical Proton Beam Using a scCVD Diamond Membrane Microdosimeter

Sensors, 2021
A single crystal chemical vapor deposition (scCVD) diamond membrane-based microdosimetric system was used to perform simultaneous measurements of dose profile and microdosimetric spectra with the Y1 proton passive scattering beamline of the Center of ...
Oluwasayo Loto, Izabella Zahradnik, Amelia Maia Leite, Ludovic De Marzi, Dominique Tromson, Michal Pomorski   +5 more
doaj   +1 more source

The Microdosimetry Analysis of a BNCT Treatment for Liver Cancer Based on PHITS Code Simulation

, 2020
Microdosimetry Analysis of a BNCT Treatment for Liver Cancer Based on PHITS Code Simulation. Cancer is a disease characterized by the growth and spread of abnormal cells that are not controlled.
Aziizah, Hasna Atqona
core   +1 more source

Comparative Evaluation of Two Analytical Functions for the Microdosimetry of Ions from ¹H to ²³⁸U

Quantum Beam Science
The analytical microdosimetric function (AMF) implemented in the Monte Carlo code PHITS is a unique tool that bridges the gap between macro- and microscopic scales of radiation interactions, enabling accurate microdosimetric calculations over macroscopic
Alessio Parisi, Keith M. Furutani, Tatsuhiko Sato, Chris J. Beltran   +3 more
doaj   +1 more source

Linking Microdosimetric Measurements to Biological Effectiveness in Ion Beam Therapy: A Review of Theoretical Aspects of MKM and Other Models

Frontiers in Physics, 2021
Different qualities of radiation are known to cause different biological effects at the same absorbed dose. Enhancements of the biological effectiveness are a direct consequence of the energy deposition clustering at the scales of DNA molecule and cell ...
V. E. Bellinzona, V. E. Bellinzona, F. Cordoni, F. Cordoni, M. Missiaggia, M. Missiaggia, F. Tommasino, F. Tommasino, E. Scifoni, C. La Tessa, C. La Tessa, A. Attili   +11 more
doaj   +1 more source

Relative Biological Effectiveness (RBE) of Monoenergetic Protons: Comparison of Empirical and Biophysical Models

Applied Sciences
A constant proton relative biological effectiveness (RBE) of 1.1 for tumor control is currently used in proton therapy treatment planning. However, in vitro, in vivo and clinical experiences indicate that proton RBE varies with kinetic energy and ...
Dimitris Dalalas, Alexis Papadopoulos, Ioanna Kyriakou, Robert D. Stewart, Pantelis Karaiskos, Dimitris Emfietzoglou   +5 more
doaj   +1 more source

Microdosimetry of kidney cells exposed to 243Am and X-ray irradiation [PDF]

EPJ Web of Conferences
In vitro experiments with rat kidney cells exposed to 243Am in cell culture medium show a decreasing cell viability with increasing americium concentration.
Kahle Pia, Senwitz Christian, Heller Anne, Seifert Anja, Taut Steffen, Kormoll Thomas   +5 more
doaj   +1 more source

Silicon 3D Microdetectors for Microdosimetry in Hadron Therapy

Micromachines, 2020
The present overview describes the evolution of new microdosimeters developed in the National Microelectronics Center in Spain (IMB-CNM, CSIC), ranging from the first ultra-thin 3D diodes (U3DTHINs) to the advanced 3D-cylindrical microdetectors, which ...
Consuelo Guardiola, Celeste Fleta, David Quirion, Giulio Pellegrini, Faustino Gómez   +4 more
doaj   +1 more source