Results 61 to 70 of about 3,468 (205)

Studies of the dose-effect relation [PDF]

, 1989
Dose-effect relations and, specifically, cell survival curves are surveyed with emphasis on the interplay of the random factors — biological variability, stochastic reaction of the cell, and the statistics of energy deposition —that co-determine their ...
A. M. Kellerer, A. M. Kellerer, A. M. Kellerer, A. M. Kellerer, A. M. Kellerer, A. M. Kellerer, A. M. Kellerer, A. M. Kellerer, C. A. Tobias, C. K. Hill, C. K. Hill, C. K. Hill, D. E. Lea, D. T. Goodhead, E. C. Pollard, E. J. Hall, E. P. Malaise, F. Dessauer, G. W. Barendsen, G. W. Barendsen, H. H. Rossi, H. H. Rossi, H. H. Rossi, H. H. Rossi, H. Withers, J. A. Crowther, J. D. Chapman, J. Fowler, J. S. Bedford, K. Günther, K. H. Chadwick, L. Hieber, M. Frankenberg-Schwager, M. M. Elkind, M. Zaider, M. Zaider, N. V. Timofeeff-Ressowsky, O. Hug, O. Hug, O. Hug, R. H. Haynes, R. P. Virsik, S. B. Curtis, S. Wolff, T. Alper, W. K. Sinclair, W. K. Sinclair, W. Pohlit   +47 more
core   +1 more source

A mechanistic‐based normal tissue complication probability (NTCP) prediction through a microdosimetry‐based multiscale radiation biophysical model (MS‐GSM2)

Precision Radiation Oncology, EarlyView.
Marco Battestini, Marta Missiaggia, Giulio Bordieri, Jules Morand, Emanuele Scifoni, Francesco Giuseppe Cordoni   +5 more
wiley   +1 more source

Experimental design and control methods for dose rate optimization in a synchrotron‐based proton therapy beamline

Precision Radiation Oncology, Volume 9, Issue 4, Page 234-241, December 2025.
Monte Carlo modeling of the geometry and particle trajectories (100 primary proton histories) without any scatterer and with different second scatterer (made of tungsten) thicknesses. Color scheme for particles: protons – blue, electrons – red, photons – green, and neutrons – yellow.
Jason Tang, Daniel Liu, Jacob Mathew, Sabrina Campelo, Lawrence Bronk, Paige Taylor, Yuting Li, Fada Guan   +7 more
wiley   +1 more source

Fast microdosimetry algorithms in particle therapy: Benchmark and applicability guidelines

Precision Radiation Oncology, EarlyView.
Giorgio Cartechini, Marta Missiaggia, Francesco Giuseppe Cordoni   +2 more
wiley   +1 more source

In silico assessment of cellular damage from Lu‐177, Ac‐225, and Pb‐212 therapeutic radionuclides

Medical Physics, Volume 52, Issue 11, November 2025.
Abstract Background Targeted radionuclide therapy (TRT) has emerged as a unique and effective treatment modality for cancer. Monte Carlo simulations have greatly advanced investigations into radiation‐caused DNA damage, including the complexity of this damage.
Konstantinos P. Chatzipapas, Konstantinos Papachristou, Dimitris Visvikis, Sebastien Incerti, John D. Hazle, George C. Kagadis   +5 more
wiley   +1 more source

Impact of Microdosimetric Modeling on Computation of Relative Biological Effectiveness for Carbon Ion Radiotherapy

Radiation
Microdosimetry plays a critical role in particle therapy by quantifying energy deposition within microscopic domains to assess biological effects. This study evaluates the influence of different microdosimetric functions (MFs) and domain geometries (DGs)
Shannon Hartzell, Keith M. Furutani, Alessio Parisi, Tatsuhiko Sato, Yuki Kase, Christian Deglow, Thomas Friedrich, Chris J. Beltran   +7 more
doaj   +1 more source

Simulating microdosimetry in a virtual hepatic lobule. [PDF]

PLoS Computational Biology, 2010
The liver plays a key role in removing harmful chemicals from the body and is therefore often the first tissue to suffer potentially adverse consequences.
John Wambaugh, Imran Shah
doaj   +1 more source

Biological implications of microdosimetry [PDF]

, 1974
Rossi, H. H., Kellerer, Albrecht M.
openaire   +5 more sources

Lineal Energy or Linear Energy Transfer? A comparative study using an SOI microdosimeter and a Timepix3 detector in a Helium‐ion pristine peak

Precision Radiation Oncology, EarlyView.
Yasmin Hamad, Sandra Barna, Tim Gehrke, Andrea Mairani   +3 more
wiley   +1 more source

Radiation quality assessment in a clinical helium-ion beam using a SOI microdosimeter and a Timepix3 detector

Frontiers in Physics
Accurate characterization of radiation quality is essential for assessing radiobiological effects in radiotherapy, yet remains a major challenge. As modern treatment strategies increasingly consider not only absorbed dose but also linear energy transfer (
Yasmin Hamad, Yasmin Hamad, Yasmin Hamad, Yasmin Hamad, Sandra Barna, Sandra Barna, Giulio Magrin, Hugo Palmans, Hugo Palmans, Ferisya Kusuma Sari, Tim Gehrke, Tim Gehrke, Tim Gehrke, Andrea Mairani, Andrea Mairani, Andrea Mairani   +15 more
doaj   +1 more source