Results 61 to 70 of about 2,193 (191)

Clonogenic Survival RBE Calculations in Carbon Ion Therapy: The Importance of the Absolute Values of α and β in the Photon Dose-Response Curve and a Strategy to Mitigate Their Anticorrelation

open access: yesQuantum Beam Science, 2023
The computation of the relative biological effectiveness (RBE) is a fundamental step in the planning of cancer radiotherapy treatments with accelerated ions.
Alessio Parisi   +2 more
doaj   +1 more source

Energy-Loss Straggling and Delta-Ray Escape in Solid-State Microdosimeters Used in Ion-Beam Therapy

open access: yesJournal of Nuclear Engineering, 2022
Microdosimetry is increasingly adopted in the characterization of proton and carbon ion beams used in cancer therapy. Spectra and mean values of lineal energy calculated in frequency and dose are seen by many as the tools which, by complementing ...
Giulio Magrin   +4 more
doaj   +1 more source

The complexity of DNA damage by radiation follows a Gamma distribution: insights from the Microdosimetric Gamma Model

open access: yesFrontiers in Oncology, 2023
IntroductionDNA damage is the main predictor of response to radiation therapy for cancer. Its Q8 quantification and characterization are paramount for treatment optimization, particularly in advanced modalities such as proton and alpha-targeted therapy ...
Alejandro Bertolet   +3 more
doaj   +1 more source

Microdosimetry and radiology Annual report, 1 Oct. 1969 - 30 Sep. 1970 [PDF]

open access: yes, 1970
Investigating experimental and theoretical approaches to microdosimetry, radiobiology, and single-scan television ...
Baily, N. A.
core  

Preparation of tissue equivalent conductive polyamide/polyethylene nanocomposite containing carbon nanotubes as electrode of the gaseous microdosimeters [PDF]

open access: yesمجله علوم و فنون هسته‌ای, 2019
The aim of this study is preparing a conductive tissue equivalent composite similar to expensive and limited access commercial A-150 plastic, in which, the Conductive Carbon Nanotubes (CNT) are used instead of black carbon.
F Khoylou   +3 more
doaj   +1 more source

Mini-TEPC Microdosimetric Study of Carbon Ion Therapeutic Beams at CNAO

open access: yesEPJ Web of Conferences, 2017
Mono-energetic carbon ion scanning beams of 195.2 MeV/u at the Italian National Centre for Oncological Hadrontherapy (CNAO) have been used to study the microdosimetric features of an “active” carbon ion beam used in hadrontherapy.
Conte V.   +5 more
doaj   +1 more source

Vision and implementation for the first U.S. carbon ion therapy center part II: Design philosophy and clinical implementation

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract The anticipated clinical demand for carbon ion radiotherapy (CIRT) in the United States is expected to include a substantial proportion of clinically complex disease sites that require accurate, highly conformal, and adaptive treatment. These clinical needs, together with the unique physical and biological characteristics of carbon ion beams ...
Xiaoying Liang, Chris J Beltran
wiley   +1 more source

Vision and implementation for the first U.S. carbon ion therapy center part I: Clinical rationale and the need for CIRT in the United States

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract Carbon ion radiotherapy (CIRT) has evolved into an established clinical modality over the past three decades. Owing to its unique physical and biological characteristics, CIRT has demonstrated favorable outcomes for selected malignancies characterized by radioresistance, proximity to critical organs, locally advanced disease requiring safe ...
Xiaoying Liang, Chris J Beltran
wiley   +1 more source

Microdosimetry of therapeutic proton beams

open access: yes, 2021
All kinds of radiotherapy treatments aim to deliver the maximum dose of radiation to the tumour cells while sparing the surrounding healthy tissues as much as possible. However, there are many cases of conventional, photon­based, radiotherapy where it is
BIANCHI, Anna
core  

A multidisciplinary experimental and methodological investigation of electron and proton minibeams in the framework of the INFN MIRO project

open access: yesMedical Physics, Volume 53, Issue 8, August 2026.
Abstract Background The clinical translation of Minibeam RT (MBRT) has recently started thanks to the first human treatments recently performed. However, despite experimental evidence, the impact of the dose distribution parameters involved on the magnitude of the effect itself and the underlying radiobiological mechanisms are still only partially ...
Francesco Romano   +89 more
wiley   +1 more source

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