Results 21 to 30 of about 298,878 (252)

Linking Microdosimetric Measurements to Biological Effectiveness in Ion Beam Therapy: A Review of Theoretical Aspects of MKM and Other Models

Frontiers in Physics, 2021
Different qualities of radiation are known to cause different biological effects at the same absorbed dose. Enhancements of the biological effectiveness are a direct consequence of the energy deposition clustering at the scales of DNA molecule and cell ...
V. E. Bellinzona, V. E. Bellinzona, F. Cordoni, F. Cordoni, M. Missiaggia, M. Missiaggia, F. Tommasino, F. Tommasino, E. Scifoni, C. La Tessa, C. La Tessa, A. Attili   +11 more
doaj   +1 more source

Microdosimetry of kidney cells exposed to 243Am and X-ray irradiation [PDF]

EPJ Web of Conferences
In vitro experiments with rat kidney cells exposed to 243Am in cell culture medium show a decreasing cell viability with increasing americium concentration.
Kahle Pia, Senwitz Christian, Heller Anne, Seifert Anja, Taut Steffen, Kormoll Thomas   +5 more
doaj   +1 more source

The relative biological effectiveness of antiprotons

Radiotherapy and Oncology, 2016
Aside from the enhancement of physical dose deposited by antiprotons annihilating in tissue-like material compared to protons of the same range a further increase of biological effective dose has been demonstrated. This enhancement can be expressed in an increase of the relative biological effectiveness (RBE) of antiprotons near the end of range.
Holzscheiter, Michael H., Alsner, Jan; id_orcid 0000-0002-5395-3193, Bassler, Niels; id_orcid 0000-0002-4160-1078, Boll, Rebecca, Caccia, Massimo, Knudsen, Helge, Maggiore, Carl, Petersen, Jørgen B., Sellner, Stefan, Strasse, Tina, Sørensen, Brita Singers; id_orcid 0000-0002-3955-4735, Overgaard, Jens   +11 more
openaire   +3 more sources

Microdosimetry Study of Proton Quality Factor Using Analytic Model Calculations

Applied Sciences, 2022
The quality factor (Q) is formally linked to the stochastic (e.g., carcinogenic) risk of diverse ionizing radiations at low doses and/or low dose rates.
Alexis Papadopoulos, Ioanna Kyriakou, Yusuke Matsuya, Sébastien Incerti, Ioannis A. Daglis, Dimitris Emfietzoglou   +5 more
doaj   +1 more source

Evaluation of the Response of HNSCC Cell Lines to γ-Rays and 12C Ions: Can Radioresistant Tumors Be Identified and Selected for 12C Ion Radiotherapy?

Frontiers in Oncology, 2022
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide. Thirty percent of patients will experience locoregional recurrence for which median survival is less than 1 year.
Lianghao Ding, Brock J. Sishc, Elizabeth Polsdofer, John S. Yordy, Angelica Facoetti, Mario Ciocca, Debabrata Saha, Arnold Pompos, Anthony J. Davis, Michael D. Story   +9 more
doaj   +1 more source

Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis (ORN) in Head and Neck Cancer Patients Treated With Pencil-Beam-Scanning Proton Therapy (PBSPT): A Retrospective, Case-Matched Cohort Study

Frontiers in Oncology, 2022
PurposeTo retrospectively investigate empirical relative biological effectiveness (RBE) for mandible osteoradionecrosis (ORN) in head and neck (H&N) cancer patients treated with pencil-beam-scanning proton therapy (PBSPT).MethodsWe included 1,266 H ...
Yunze Yang, Olivia M. Muller, Satomi Shiraishi, Matthew Harper, Adam C. Amundson, William W. Wong, Lisa A. McGee, Jean-Claude M. Rwigema, Steven E. Schild, Martin Bues, Mirek Fatyga, Justin D. Anderson, Samir H. Patel, Robert L. Foote, Wei Liu   +14 more
doaj   +1 more source

Biophysical modeling and experimental validation of relative biological effectiveness (RBE) for 4He ion beam therapy

Radiation Oncology, 2019
Background Helium (4He) ion beam therapy provides favorable biophysical characteristics compared to currently administered particle therapies, i.e., reduced lateral scattering and enhanced biological damage to deep-seated tumors like heavier ions, while ...
Stewart Mein, Ivana Dokic, Carmen Klein, Thomas Tessonnier, Till Tobias Böhlen, Guiseppe Magro, Julia Bauer, Alfredo Ferrari, Katia Parodi, Thomas Haberer, Jürgen Debus, Amir Abdollahi, Andrea Mairani   +12 more
doaj   +1 more source

METHODS OF ASSESSMENT OF THE RELATIVE BIOLOGICAL EFFECTIVENESS OF NEUTRONS IN NEUTRON THERAPY

Сибирский онкологический журнал, 2017
The relative biological effectiveness (RBE) of fast neutrons is an important factor influencing the quality of neutron therapy therefore, the assessment of RBE is of great importance.
V. A. Lisin
doaj   +1 more source

Relative Biological Effectiveness (RBE) of 131I Radiation Relative to 60Co Gamma Rays [PDF]

Cell Journal, 2013
Objective: To assess relative biological effectiveness (RBE) of 131I radiation relative to 60Co gamma rays in glioblastoma spheroid cells.Materials and Methods: In this experimental study, glioblastoma spheroid cells were exposed to 131I radiation and ...
Seyed Rabie Mahdavi, Ali Mahmoud Pashazadeh, Ali Neshasteh-Riz   +2 more
doaj  

Estimating the Relative Biological Effectiveness of Auger Electron Emitter 123I in Human Lymphocytes

Frontiers in Physics, 2020
Auger electron emitters are considered to be a promising strategy for targeted radionuclide therapy of metastatic diseases, given their high linear energy transfer (LET) and short range in tissue which could potentially limit normal tissue toxicity ...
Hein Fourie, Shankari Nair, Xanthene Miles, Daniel Rossouw, Philip Beukes, Richard T. Newman, Jan Rijn Zeevaart, Charlot Vandevoorde, Jacobus Slabbert   +8 more
doaj   +1 more source