Results 21 to 30 of about 885,465 (288)

Mapping the Relative Biological Effectiveness of Proton, Helium and Carbon Ions with High-Throughput Techniques. [PDF]

open access: yesCancers (Basel), 2020
Bronk L   +14 more
europepmc   +2 more sources

Microdosimetry Study of Proton Quality Factor Using Analytic Model Calculations

open access: yesApplied Sciences, 2022
The quality factor (Q) is formally linked to the stochastic (e.g., carcinogenic) risk of diverse ionizing radiations at low doses and/or low dose rates.
Alexis Papadopoulos   +5 more
doaj   +1 more source

Proton relative biological effectiveness (RBE): a multiscale problem. [PDF]

open access: yesBr J Radiol, 2019
Proton radiotherapy is undergoing rapid expansion both within the UK and internationally, but significant challenges still need to be overcome if maximum benefit is to be realised from this technique. One major limitation is the persistent uncertainty in proton relative biological effectiveness (RBE).
Underwood TS, McMahon SJ.
europepmc   +6 more sources

Evaluation of the Response of HNSCC Cell Lines to γ-Rays and 12C Ions: Can Radioresistant Tumors Be Identified and Selected for 12C Ion Radiotherapy?

open access: yesFrontiers in Oncology, 2022
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide. Thirty percent of patients will experience locoregional recurrence for which median survival is less than 1 year.
Lianghao Ding   +9 more
doaj   +1 more source

Rapid RBE-Weighted Proton Radiation Dosimetry Risk Assessment [PDF]

open access: yes, 2016
Proton therapy dose is affected by relative biological effectiveness differently than X-ray therapies. The current clinically accepted weighting factor is 1.1 at all positions along the depth–dose profile.
Buchsbaum, Jeffrey C.   +2 more
core   +1 more source

Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis (ORN) in Head and Neck Cancer Patients Treated With Pencil-Beam-Scanning Proton Therapy (PBSPT): A Retrospective, Case-Matched Cohort Study

open access: yesFrontiers in Oncology, 2022
PurposeTo retrospectively investigate empirical relative biological effectiveness (RBE) for mandible osteoradionecrosis (ORN) in head and neck (H&N) cancer patients treated with pencil-beam-scanning proton therapy (PBSPT).MethodsWe included 1,266 H ...
Yunze Yang   +14 more
doaj   +1 more source

Clinical consequences of relative biological effectiveness variations in proton radiotherapy of the prostate, brain and liver [PDF]

open access: yes, 2013
Proton relative biological effectiveness (RBE) is known to depend on the (alpha/beta)(x) of irradiated tissues, with evidence of similar to 60% variation over (alpha/beta)(x) values from 1-10 Gy.
Carabe, Alejandro   +3 more
core   +1 more source

The relative biological effectiveness of antiprotons

open access: yesRadiotherapy and Oncology, 2016
Aside from the enhancement of physical dose deposited by antiprotons annihilating in tissue-like material compared to protons of the same range a further increase of biological effective dose has been demonstrated. This enhancement can be expressed in an increase of the relative biological effectiveness (RBE) of antiprotons near the end of range.
Holzscheiter, Michael H.   +11 more
openaire   +3 more sources

Basics of particle therapy II: relative biological effectiveness [PDF]

open access: yesRadiation Oncology Journal, 2012
In the previous review, the physical aspect of heavy particles, with a focus on the carbon beam was introduced. Particle beam therapy has many potential advantages for cancer treatment without increasing severe side effects in normal tissue, these kinds of radiation have different biologic characteristics and have advantages over using conventional ...
Choi, Jinhyun, Kang, Jin Oh
openaire   +2 more sources

Estimating the Relative Biological Effectiveness of Auger Electron Emitter 123I in Human Lymphocytes

open access: yesFrontiers in Physics, 2020
Auger electron emitters are considered to be a promising strategy for targeted radionuclide therapy of metastatic diseases, given their high linear energy transfer (LET) and short range in tissue which could potentially limit normal tissue toxicity ...
Hein Fourie   +8 more
doaj   +1 more source

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