Results 31 to 40 of about 8,300,360 (253)

Relative Biological Effectiveness Variation Along Monoenergetic and Modulated Bragg Peaks of a 62-MeV Therapeutic Proton Beam: A Preclinical Assessment [PDF]

, 2014
iological optimization of proton therapy critically depends on detailed evaluation of relative biological effectiveness (RBE) variations along the Bragg curve.
Romano, Francesco, Perozziello, Francesca M, Prise, Kevin M., Schettino, Giuseppe, Cirrone, Giuseppe Antonio Pablo, McMahon, Stephen J., Kavanagh, Joy N, Hanton, Fiona, Prise, Kevin M; id_orcid, I Marshall, Thomas, Manti, Lorenzo, Currell, Frederick J, Chaudhary, Pankaj, Currell, Frederick J.; id_orcid, McMahon, Stephen J; id_orcid, Marshall, Thomas I., Kavanagh, Joy N., Perozziello, Francesca M., Chaudhary P, Schettino G., Marshall TI, Kavanagh JN, Cirrone GAP, Prise KM, Romano F, Perozziello, Francesca Margaret, McMahon SJ, Hanton F, Currell FJ   +28 more
core   +1 more source

Cost-effectiveness of biological treatment of ulcerative colitis – a systematic review [PDF]

, 2017
The aim of this systematic review was to collect and summarise all current data on the cost-effectiveness of biological treatment in ulcerative colitis.
Stawowczyk, Ewa, Kawalec, Paweł, Paweł Kawalec, Ewa Stawowczyk   +3 more
core   +1 more source

In vitro measurement of proton RBE: A multi-centric comparison using a harmonized setup

Clinical and Translational Radiation Oncology
Background and purpose: This study presents a multi-center comparison of in vitro cell survival measurements and RBE calculations following proton irradiations conducted under harmonized experimental conditions across six European institutions ...
Olga Sokol, Anders Tobias Frederiksen, Mateusz Sitarz, Brita Singers Sørensen, Elham Santina, Christopher Smith, John-William Warmenhoven, Marie Davídková, Anna Jelínek Michaelidesová, Irina Danilová, Oldřich Zahradníček, Amélia Maia Leite, Ludovic de Marzi, Frederic Pouzoulet, Paweł Olko, Justyna Miszczyk, Barbara Orzechowska, Eleftherios Papalanis, Mehran Hariri, Diana Spiegelberg, Bo Stenerlöw, Alexandru Dasu, Elisabeth Bodenstein, Elke Beyreuther, Jörg Pawelke, Dorothee Pfitzmann, Karen Kirkby, Nicholas Henthorn, Marco Durante   +28 more
doaj   +1 more source

Repeatability and Reproducibility of Microdosimetry With a Mini-TEPC

Frontiers in Physics, 2021
Experimental microdosimetry measures the energy deposited in a microscopic sensitive volume (SV) by single ionizing particles traversing the SV or passing by.
A. Bianchi, A. Bianchi, A. Bianchi, A. Selva, P. Colautti, G. Petringa, P. Cirrone, B. Reniers, A. Parisi, F. Vanhavere, V. Conte   +10 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Microdosimetry test on double layer beam shaping assembly neutron beam as a boron neutron capture therapy neutron source using PHITS code [PDF]

Ядерна фізика та енергетика
A microdosimetry test on a double layer beam shaping assembly (DLBSA) neutron beam has been carried out using the particle and heavy ion transport code system (PHITS).
Bilalodin, A. Haryadi, Sehah, Zusfahair, Y. Sardjono, R. Tursinah   +5 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Effect of relative biological effectiveness as a function of the cell-specific repair rate (a + c) (T = 60 min).

, 2018
Effect of relative biological effectiveness as a function of the cell-specific repair rate (a + c) (T = 60 min).
Daisuke Kawahara (6000239), Kaoru Ono (1969618), Yukio Akagi (6000242), Yutaka Hirokawa (6000245), Hisashi Nakano (6000236)   +4 more
core   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source