Results 31 to 40 of about 298,878 (252)

Relative Biological Effectiveness (RBE) of Monoenergetic Protons: Comparison of Empirical and Biophysical Models

Applied Sciences
A constant proton relative biological effectiveness (RBE) of 1.1 for tumor control is currently used in proton therapy treatment planning. However, in vitro, in vivo and clinical experiences indicate that proton RBE varies with kinetic energy and ...
Dimitris Dalalas, Alexis Papadopoulos, Ioanna Kyriakou, Robert D. Stewart, Pantelis Karaiskos, Dimitris Emfietzoglou   +5 more
doaj   +1 more source

Repeatability and Reproducibility of Microdosimetry With a Mini-TEPC

Frontiers in Physics, 2021
Experimental microdosimetry measures the energy deposited in a microscopic sensitive volume (SV) by single ionizing particles traversing the SV or passing by.
A. Bianchi, A. Bianchi, A. Bianchi, A. Selva, P. Colautti, G. Petringa, P. Cirrone, B. Reniers, A. Parisi, F. Vanhavere, V. Conte   +10 more
doaj   +1 more source

(Theory of relative biological effectiveness) [PDF]

, 1992
Research continued on relative biological effectiveness, in the following areas: radial distribution of dose about the path of an energetic heavy ion; the response of E. Coli mutants to ionizing radiations; the application of a fragmentation model to to the calculation of cell survival and mutation with heavy ion beams; biological radiation effects ...
openaire   +2 more sources

In vitro measurement of proton RBE: A multi-centric comparison using a harmonized setup

Clinical and Translational Radiation Oncology
Background and purpose: This study presents a multi-center comparison of in vitro cell survival measurements and RBE calculations following proton irradiations conducted under harmonized experimental conditions across six European institutions ...
Olga Sokol, Anders Tobias Frederiksen, Mateusz Sitarz, Brita Singers Sørensen, Elham Santina, Christopher Smith, John-William Warmenhoven, Marie Davídková, Anna Jelínek Michaelidesová, Irina Danilová, Oldřich Zahradníček, Amélia Maia Leite, Ludovic de Marzi, Frederic Pouzoulet, Paweł Olko, Justyna Miszczyk, Barbara Orzechowska, Eleftherios Papalanis, Mehran Hariri, Diana Spiegelberg, Bo Stenerlöw, Alexandru Dasu, Elisabeth Bodenstein, Elke Beyreuther, Jörg Pawelke, Dorothee Pfitzmann, Karen Kirkby, Nicholas Henthorn, Marco Durante   +28 more
doaj   +1 more source

Microdosimetry test on double layer beam shaping assembly neutron beam as a boron neutron capture therapy neutron source using PHITS code [PDF]

Ядерна фізика та енергетика
A microdosimetry test on a double layer beam shaping assembly (DLBSA) neutron beam has been carried out using the particle and heavy ion transport code system (PHITS).
Bilalodin, A. Haryadi, Sehah, Zusfahair, Y. Sardjono, R. Tursinah   +5 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source

The history of ion beam therapy in Germany

Zeitschrift für Medizinische Physik, 2022
The advantageous depth dose profile of ion beams together with state of the art beam delivery and treatment planning systems allow for highly conformal tumor treatments in patients.
Oliver Jäkel, Gerhard Kraft, Christian P. Karger   +2 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Macro- and Micro-scale Dose Simulation of Heavy Ion Relative Biological Effectiveness

Yuanzineng kexue jishu
Heavy ion therapy is an important cancer treatment. Accurate evaluation of the biophysical effects of heavy ions is of great significance to improve the refinement level of particle radiotherapy.
HU Ziyi1,2, QIU Rui1,2, CHEN Yizheng4, HU Ankang1,2, WU Zhen1,3, ZHANG Hui1,2, LI Junli1,2
doaj   +1 more source