Results 1 to 10 of about 11,143 (172)

Combined carbon ion radiotherapy and immunotherapy: leveraging the immunological advantages of carbon ion [PDF]

Frontiers in Immunology
Immunotherapy represents a systemic approach to cancer treatment; however, its effectiveness can be limited by intrinsic tumor resistance or immunosuppressive mechanisms within the tumor microenvironment.
Ruiming Chen, Qinqin Ma, Yuan Pan, Tanglong Zhang, Zhuoya Zhang, Cuixia Di, Juntao Ran   +6 more
doaj   +2 more sources

Carbon ion radiotherapy for unresectable localized axial soft tissue sarcoma

Cancer Medicine, 2018
Carbon ion radiotherapy is known for its high‐precision dose distribution and high biological effectiveness. We evaluated the results of carbon ion radiotherapy in 128 patients with unresectable localized axial soft tissue sarcoma at a single institution.
Reiko Imai, Tadashi Kamada, Nobuhito Araki, and the Working Group for Carbon Ion Radiotherapy for Bone and Soft Tissue Sarcomas   +3 more
doaj   +2 more sources

Landscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research

Frontiers in Oncology, 2021
Carbon ion radiotherapy (CIRT) is a useful and advanced technique for prostate cancer. This study sought to investigate the clinical efficacy and translational research for prostate cancer with carbon ion radiotherapy.
Xue Chen, Xue Chen, Qi Yu, Qi Yu, Qi Yu, Qi Yu, Ping Li, Shen Fu, Shen Fu, Shen Fu, Shen Fu, Shen Fu   +11 more
doaj   +1 more source

Clinical outcomes using carbon-ion radiotherapy and dose-volume histogram comparison between carbon-ion radiotherapy and photon therapy for T2b-4N0M0 non-small cell lung cancer-A pilot study. [PDF]

PLoS ONE, 2017
The safety and efficacy of carbon-ion radiotherapy for advanced non-small cell lung cancer have not been established. We evaluated the clinical outcomes and dose-volume histogram parameters of carbon-ion radiotherapy compared with photon therapy in T2b ...
Katsuyuki Shirai, Motohiro Kawashima, Jun-Ichi Saitoh, Takanori Abe, Kyohei Fukata, Yuka Shigeta, Daisuke Irie, Shintaro Shiba, Naoko Okano, Tatsuya Ohno, Takashi Nakano   +10 more
doaj   +1 more source

In vitro evaluation of photon and carbon ion radiotherapy in combination with cisplatin in head and neck squamous cell carcinoma cell lines

Frontiers in Oncology, 2023
BackgroundHeavy ion radiotherapy, such as carbon ion radiotherapy (CIRT), has multiple advantages over conventional photon therapy. Cisplatin, as a classic anti-tumor drugs, has been tested and discovered as a photon radiosensitizer in several cell lines,
Xumeng Fang, Xumeng Fang, Xumeng Fang, Pian Sun, Pian Sun, Pian Sun, Yuanli Dong, Yuanli Dong, Yuanli Dong, Yangle Huang, Yangle Huang, Yangle Huang, Jiade Jay Lu, Jiade Jay Lu, Jiade Jay Lu, Lin Kong, Lin Kong, Lin Kong   +17 more
doaj   +1 more source

Functional imaging-guided carbon ion irradiation with simultaneous integrated boost for localized prostate cancer: study protocol for a phase II randomized controlled clinical trial

Trials, 2022
Background Due to the physical dose distribution characteristic of “Bragg peak” and the biological effect as a kind of high linear energy transfer ray, heavy ion therapy has advantages over conventional photon therapy in both efficacy and safety.
Wei Hu, Ping Li, Zhengshan Hong, Xiaomao Guo, Yulei Pei, Zhenshan Zhang, Qing Zhang   +6 more
doaj   +1 more source

Carbon Ion Therapy: A Modern Review of an Emerging Technology

Frontiers in Oncology, 2020
Radiation therapy is one of the most widely used therapies for malignancies. The therapeutic use of heavy ions, such as carbon, has gained significant interest due to advantageous physical and radiobiologic properties compared to photon based therapy. By
Timothy D. Malouff, Anita Mahajan, Sunil Krishnan, Chris Beltran, Danushka S. Seneviratne, Daniel Michael Trifiletti   +5 more
doaj   +1 more source

Genetic Analysis of T Cell Lymphomas in Carbon Ion-Irradiated Mice Reveals Frequent Interstitial Chromosome Deletions: Implications for Second Cancer Induction in Normal Tissues during Carbon Ion Radiotherapy. [PDF]

PLoS ONE, 2015
Monitoring mice exposed to carbon ion radiotherapy provides an indirect method to evaluate the potential for second cancer induction in normal tissues outside the radiotherapy target volume, since such estimates are not yet possible from historical ...
Benjamin J Blyth, Shizuko Kakinuma, Masaaki Sunaoshi, Yoshiko Amasaki, Shinobu Hirano-Sakairi, Kanae Ogawa, Ayana Shirakami, Yi Shang, Chizuru Tsuruoka, Mayumi Nishimura, Yoshiya Shimada   +10 more
doaj   +1 more source

Preliminary Safety and Efficacy of Proton Plus Carbon-Ion Radiotherapy With Concurrent Chemotherapy in Limited-Stage Small Cell Lung Cancer

Frontiers in Oncology, 2021
ObjectivesThis study aimed to investigate the tolerance and effect of proton plus carbon-ion radiotherapy with concurrent chemotherapy in limited-stage small cell lung cancer using the pencil beam scanning technique.Materials and MethodsFrom March 2017 ...
Ning-Yi Ma, Ning-Yi Ma, Ning-Yi Ma, Jian Chen, Jian Chen, Jian Chen, Xue Ming, Xue Ming, Xue Ming, Guo-Liang Jiang, Guo-Liang Jiang, Guo-Liang Jiang, Jiade J. Lu, Jiade J. Lu, Jiade J. Lu, Kai-Liang Wu, Kai-Liang Wu, Kai-Liang Wu, Jingfang Mao, Jingfang Mao, Jingfang Mao   +20 more
doaj   +1 more source

Flourish of Proton and Carbon Ion Radiotherapy in China

Frontiers in Oncology, 2022
Proton and heavy ion therapy offer superior relative biological effectiveness (RBE) in the treatment of deep-seated tumors compared with conventional photon radiotherapy due to its Bragg-peak feature of energy deposition in organs. Many proton and carbon
Yue Li, Xiaoman Li, Jiancheng Yang, Sicheng Wang, Meitang Tang, Jiawen Xia, Jiawen Xia, Yunzhe Gao, Yunzhe Gao   +8 more
doaj   +1 more source