Results 1 to 10 of about 1,102,765 (304)

Combined carbon ion radiotherapy and immunotherapy: leveraging the immunological advantages of carbon ion [PDF]

Frontiers in Immunology
Immunotherapy represents a systemic approach to cancer treatment; however, its effectiveness can be limited by intrinsic tumor resistance or immunosuppressive mechanisms within the tumor microenvironment.
Ruiming Chen, Qinqin Ma, Yuan Pan, Tanglong Zhang, Zhuoya Zhang, Cuixia Di, Juntao Ran   +6 more
doaj   +2 more sources

Carbon Ion Radiobiology [PDF]

Cancers, 2020
Radiotherapy using accelerated charged particles is rapidly growing worldwide. About 85% of the cancer patients receiving particle therapy is irradiated with protons, which have physical advantages compared to X-rays but similar biological response. In addition to the ballistic advantages, heavy ions present specific radiobiological features that can ...
Tinganelli W., Durante M.
openaire   +5 more sources

Preliminary Safety and Efficacy of Proton Plus Carbon-Ion Radiotherapy With Concurrent Chemotherapy in Limited-Stage Small Cell Lung Cancer

Frontiers in Oncology, 2021
ObjectivesThis study aimed to investigate the tolerance and effect of proton plus carbon-ion radiotherapy with concurrent chemotherapy in limited-stage small cell lung cancer using the pencil beam scanning technique.Materials and MethodsFrom March 2017 ...
Ning-Yi Ma, Ning-Yi Ma, Ning-Yi Ma, Jian Chen, Jian Chen, Jian Chen, Xue Ming, Xue Ming, Xue Ming, Guo-Liang Jiang, Guo-Liang Jiang, Guo-Liang Jiang, Jiade J. Lu, Jiade J. Lu, Jiade J. Lu, Kai-Liang Wu, Kai-Liang Wu, Kai-Liang Wu, Jingfang Mao, Jingfang Mao, Jingfang Mao   +20 more
doaj   +1 more source

Carbon ions induce DNA double strand breaks and apoptosis in HTB140 melanoma cells [PDF]

Nuclear Technology and Radiation Protection, 2013
This study was conducted in order to evaluate the ability of carbon ions to induce DNA double-strand breaks and apoptosis in the radio-resistant human HTB140 melanoma cells.
Korićanac Lela, Žakula Jelena, Keta Otilija, Cirrone Pablo, Cuttone Giacomo, Ristić-Fira Aleksandra, Petrović Ivan   +6 more
doaj   +1 more source

The Potentiation of Anti-Tumor Immunity by Tumor Abolition with Alpha Particles, Protons, or Carbon Ion Radiation and Its Enforcement by Combination with Immunoadjuvants or Inhibitors of Immune Suppressor Cells and Checkpoint Molecules

Cells, 2021
The delivery of radiation therapy (RT) for cancer with intent to cure has been optimized and standardized over the last 80 years. Both preclinical and clinical work emphasized the observation that radiation destroys the tumor and exposes its components ...
Yona Keisari, Itzhak Kelson
doaj   +1 more source

Preliminary clinical outcomes of head and neck squamous cell carcinoma treated with particle beam radiation therapy

Cancer Medicine, 2023
Purpose Further improvement in clinical outcomes is needed for patients with head and neck squamous cell carcinoma (HNSCC), as there is typically a poor prognosis at diagnosis.
Qingting Huang, Jiyi Hu, Weixu Hu, Jing Gao, Jing Yang, Xianxin Qiu, Haojiong Zhang, Jiade Jay Lu, Lin Kong   +8 more
doaj   +1 more source

Types and Incidence of Moderate and Severe Toxic Effects of Carbon Ion Radiotherapy for Head and Neck Cancer

Zhongliu Fangzhi Yanjiu, 2023
Head and neck tumors often have complex anatomical structures and are adjacent to important organs. Radiation injury caused by conventional radiotherapy technology is the main dose-limiting factor.
YANG Pengcheng, YAO Yi, LEI Tianyu, HU Qinyong   +3 more
doaj   +1 more source

Computational high-throughput screening of alloy nanoclusters for electrocatalytic hydrogen evolution

npj Computational Materials, 2021
Here, we report a density functional theory (DFT)-based high-throughput screening method to successfully identify a type of alloy nanoclusters as the electrocatalyst for hydrogen evolution reaction (HER).
Xinnan Mao, Lu Wang, Yafeng Xu, Pengju Wang, Youyong Li, Jijun Zhao   +5 more
doaj   +1 more source

Influence of photon, proton and carbon ion irradiation on differentiation, maturation and functionality of dendritic cells

Frontiers in Bioscience-Scholar, 2022
While the primary purpose of radiotherapy (RT) is the elimination of cancer cells by inducing DNA-damage, considerable evidence emerges that anti-neoplastic effects extend beyond mere tumor cell killing. These secondary effects are based on activation of
Laila König, Adriane Hommertgen, Lena Orschiedt, Juliane Hörner-Rieber, Stephan Brons, Peter E. Huber, Jürgen Debus, Stefan Rieken   +7 more
doaj   +1 more source

Safety and Efficacy of Carbon Ion and Proton Therapies for Pancreatic Cancer: A Systematic Review and Meta-analysis

Zhongliu Fangzhi Yanjiu, 2020
Objective To evaluate the safety and efficacy of carbon ion and proton therapies for pancreatic cancer (PaC). Methods The databases were electronically searched to collect the studies about the carbon ion and proton therapies for PaC from inception to ...
LIAO Yiran, ZHANG Qiuning, SHAO Lihua, LIU Ruifeng, LUO Hongtao, WANG Lina, FENG Shuangwu, YANG Kehu, WANG Xiaohu   +8 more
doaj   +1 more source