Results 21 to 30 of about 363,438 (266)

FLASH radiotherapy with carbon ion beams [PDF]

Medical Physics, 2021
AbstractFLASH radiotherapy is considered a new potential breakthrough in cancer treatment. Ultra‐high dose rates (>40 Gy/s) have been shown to reduce toxicity in the normal tissue without compromising tumor control, resulting in a widened therapeutic window.
Weber U. A., Scifoni E., Durante M.
openaire   +6 more sources

Technical Note: Improving the workflow in a carbon ion therapy center with custom software for enhanced patient care

Technical Innovations & Patient Support in Radiation Oncology
Carbon-ion radiation therapy (CIRT) is an up-and-coming modality for cancer treatment. Implementation of CIRT requires collaboration among specialists like radiation oncologists, medical physicists, and other healthcare professionals.
Sridhar Yaddanapudi, Yushi Wakisaka, Keith M. Furutani, Masashi Yagi, Shinichi Shimizu, Chris J. Beltran   +5 more
doaj   +1 more source

Carbonions and Proton Therapy for Hepatocellular Carcinoma: A Meta-analysis

Zhongliu Fangzhi Yanjiu, 2020
Objective To evaluate the efficacy and safety of carbon ion and proton therapy for hepatocellular carcinoma (HCC) by Meta-analysis. Methods PubMed, The Cochrane Library, EMBASE, Chinese Journal Full-text, Chinese Biomedical Literature and Wanfang ...
SHAO Lihua, ZHANG Qiuning, LUO Hongtao, YANG Zhen, LIU Ruifeng, TIAN Jinhui, LI Zheng, WANG Xiaohu, YANG Kehu   +8 more
doaj   +1 more source

Revisiting the critical role of metallic ash elements in the development of hard carbon for advancing sodium-ion battery applications

eScience
Hard carbon (HC) anodes in sodium-ion batteries (SIBs) are prized for their high capacity, durability, cost-efficiency, environmental sustainability, and safety. The metallic ash elements in HCs inevitably affect the overall performance of SIBs, however,
Chun Wu, Wenjie Huang, Yinghao Zhang, Qinghang Chen, Li Li, Yajun Zhang, Xingqiao Wu, Shu-Lei Chou   +7 more
doaj   +1 more source

Landscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research

Frontiers in Oncology, 2021
Carbon ion radiotherapy (CIRT) is a useful and advanced technique for prostate cancer. This study sought to investigate the clinical efficacy and translational research for prostate cancer with carbon ion radiotherapy.
Xue Chen, Xue Chen, Qi Yu, Qi Yu, Qi Yu, Qi Yu, Ping Li, Shen Fu, Shen Fu, Shen Fu, Shen Fu, Shen Fu   +11 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Dosimetric impact of stopping power for human bone porosity with dual-energy computed tomography in scanned carbon-ion therapy treatment planning

Scientific Reports
Few reports have documented how the accuracy of stopping power ratio (SPR) prediction for porous bone tissue affects the dose distribution of scanned carbon-ion beam therapy.
Masashi Yagi, Yushi Wakisaka, Jun Takeno, Shintaro Kanada, Toshiro Tsubouchi, Noriaki Hamatani, Hiroyasu Maruo, Masaaki Takashina, Takayoshi Ishii, Tatsuaki Kanai, Shinichi Shimizu, Kazuhiko Ogawa   +11 more
doaj   +1 more source

The Combination of Particle Irradiation With the Hedgehog Inhibitor GANT61 Differently Modulates the Radiosensitivity and Migration of Cancer Cells Compared to X-Ray Irradiation

Frontiers in Oncology, 2019
Due to the advantages of charged particles compared to conventional radiotherapy, a vast increase is noted in the use of particle therapy in the clinic.
Katrien Konings, Katrien Konings, Charlot Vandevoorde, Niels Belmans, Niels Belmans, Randy Vermeesen, Bjorn Baselet, Merel Van Walleghem, Ann Janssen, Sofie Isebaert, Sofie Isebaert, Sarah Baatout, Karin Haustermans, Karin Haustermans, Marjan Moreels   +14 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source