Results 41 to 50 of about 1,102,765 (304)

Carbon-ion Radiotherapy for Colorectal Cancer

Journal of the Anus, Rectum and Colon, 2021
Heavy-ion radiotherapy (RT) is a kind of particle RT, and carbon-ion beam constitutes the primary delivery method of heavy-ion RT. Unlike the conventional photon modalities, particle RT, in particular carbon-ion radiotherapy (CIRT), offers unique physical and biological advantages.
Shigeru Yamada, Hirotoshi Takiyama, Yuka Isozaki, Makoto Shinoto, Hirokazu Makishima, Naoyoshi Yamamoto, Hiroshi Tsuji   +6 more
openaire   +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Charged Particle Irradiation for Pancreatic Cancer: A Systematic Review of In Vitro Studies

Frontiers in Oncology, 2022
PurposeGiven the higher precision accompanied by optimized sparing of normal tissue, charged particle therapy was thought of as a promising treatment for pancreatic cancer. However, systematic preclinical studies were scarce.
Dandan Wang, Dandan Wang, Ruifeng Liu, Ruifeng Liu, Ruifeng Liu, Qiuning Zhang, Qiuning Zhang, Qiuning Zhang, Hongtao Luo, Hongtao Luo, Hongtao Luo, Junru Chen, Junru Chen, Meng Dong, Meng Dong, Yuhang Wang, Yuhang Wang, Yuhong Ou, Yuhong Ou, Zhiqiang Liu, Zhiqiang Liu, Zhiqiang Liu, Shilong Sun, Shilong Sun, Shilong Sun, Kehu Yang, Jinhui Tian, Zheng Li, Xiaohu Wang, Xiaohu Wang, Xiaohu Wang, Xiaohu Wang   +31 more
doaj   +1 more source

Biomass-derived carbon materials for energy storage applications [PDF]

, 2021
Energy storage systems are an essential link in the implementation of renewable energies and in the development of electric vehicles, which are needed to reduce our dependence on fossil fuels and the emission of greenhouse gases.
Gómez Martín, Aurora
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Helium-3 and Helium-4 acceleration by high power laser pulses for hadron therapy

, 2015
The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized ...
Bulanov, S. S., Bulanov, S. V., Esarey, E., Haberer, T., Korn, G., Leemans, W. P., Margarone, D., Schroeder, C. B.   +7 more
core   +2 more sources

Ion Beam Analyses of Carbon Nanotubes [PDF]

The Journal of Physical Chemistry B, 2005
The utility of ion beam analysis (IBA) techniques to quantitatively determine impurities in carbon nanotubes (CNTs) over a wide range of atomic numbers is demonstrated. Such techniques have not previously been used to monitor impurities and their effects in this unique material. Despite the difficulty in mounting the samples (which generally are formed
Naab, Fabian U., Holland, Orin W., Duggan, Jerome L., McDaniel, Floyd Del. (Floyd Delbert)   +4 more
openaire   +3 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Carbon ion radiotherapy for recurrent ameloblastoma: A case report

SAGE Open Medical Case Reports, 2022
Ameloblastoma is a kind of benign, odontogenic tumor of epithelial origin, and surgery is mainstay treatment method; however, recurrence is common, and usually the treatment for recurrence is still surgery.
Yihe Zhang, Xiaojun Li, Yanshan Zhang, Yancheng Ye, Xin Pan, Tingchao Hu, Weizuo Chen, Hongyu Chai, Xin Wang, Yuling Yang   +9 more
doaj   +1 more source

Deposition of diamondlike carbon films [PDF]

, 1984
A diamondlike carbon film is deposited in the surface of a substrate by exposing the surface to an argon ion beam containing a hydrocarbon. The current density in the ion beam is low during initial deposition of the film.
Banks, B. A., Mirtich, M. J., Sovey, J. S.   +2 more
core   +1 more source