Results 61 to 70 of about 2,488,526 (298)

Darbepoetin alfa given every 1 or 2 weeks alleviates anaemia associated with cancer chemotherapy. [PDF]

, 2002
In part A of this study, patients were randomised to cohorts receiving darbepoetin alfa at doses of 0.5 to 8.0 m.c.g x kg(-1) x wk(-1) or to a control group receiving epoetin alfa at an initial dose of 150 U x kg(-1) three times weekly.
Armstrong, S, Colowick, AB, Glaspy, JA, Jadeja, JS, Justice, G, Kessler, J, O'Byrne, J, Richards, D, Rossi, G, Schwartzberg, L, Tchekmedyian, NS   +10 more
core   +2 more sources

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Response-adaptive dose-finding under model uncertainty [PDF]

, 2010
Dose-finding studies are frequently conducted to evaluate the effect of different doses or concentration levels of a compound on a response of interest.
At Bochum, Björn Bornkamp, Frank Bretz, Holger Dette, Jose ́ Pinheiro   +4 more
core   +3 more sources

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Evaluation of levels of exposure of adult patients from common radiographic examinations in the Russian Federation in 2009–2014

Радиационная гигиена, 2017
Diagnostic reference levels are the main and the most effective tools of optimization of the radiation protection of patients from medical exposure.
A. V. Vodovatov, V. Yu. Golikov, S. A. Kalnitsky, I. G. Shatsky, L. A. Chipiga   +4 more
doaj   +1 more source

A revised compartmental model for biokinetics and dosimetry of 2-[18F]FDG

EJNMMI Physics, 2023
Background The aim was to review available biokinetic data, collect own experimental data, and propose an updated compartmental model for 2-[18F]FDG in the frame of the revision of the ICRP report on dose coefficients for radiopharmaceuticals used in ...
Alexandra Kamp, Martin Andersson, Sigrid Leide-Svegborn, Dietmar Noβke, Sören Mattsson, Augusto Giussani   +5 more
doaj   +1 more source

PTV margin for dose escalated radiation therapy of prostate cancer with daily on-line realignment using internal fiducial markers: Monte Carlo approach and dose population histogram (DPH) analysis. [PDF]

, 2006
Using internal fiducial markers and electronic portal imaging (EPID) to realign patients has been shown to significantly reduce positioning uncertainties in prostate radiation treatment.
Liu, Mitchell, Moiseenko, Vitali, Zhang, Miao   +2 more
core   +1 more source

Effective dose from radiopharmaceuticals [PDF]

European Journal of Nuclear Medicine, 1992
The effective dose, as defined by the International Commission on Radiological Protection (ICRP 1991), provides a possibility of expressing the radiation risk to patients undergoing different radiodiagnostic procedures by means of a single figure.
L, Johansson, S, Mattsson, B, Nosslin, S, Leide-Svegborn   +3 more
openaire   +2 more sources

Hypnosis for acute procedural pain: a critical review [PDF]

, 2014
Clinical evidence for the effectiveness of hypnosis in the treatment of acute procedural pain was critically evaluated based on reports from randomized controlled clinical trials (RCTs).
Elkins, G, Fisher, W, Johnson, A, Kekecs, Z, Kendrick, C, Sliwinski, J, Yu, Y   +6 more
core   +1 more source