Results 111 to 120 of about 115,577 (299)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Chiral kinetic theory from effective field theory revisited

Journal of High Energy Physics, 2019
We revisit the chiral kinetic equation from high density effective theory approach, finding a chiral kinetic equation differs from counterpart derived from field theory in high order terms in the O(1/μ) expansion, but in agreement with the equation ...
Shu Lin, Aradhya Shukla
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Generalized T T ¯ $$ T\overline{T} $$ -like deformations in duality-invariant nonlinear electrodynamic theories

Journal of High Energy Physics
This study introduces a high-order perturbation methodology to categorize two primary solution types within duality-invariant nonlinear electrodynamic theories, adhering to the differential self-duality criterion.
H. Babaei-Aghbolagh, Song He, Hao Ouyang
doaj   +1 more source

Off-shell renormalization in Higgs effective field theories

Journal of High Energy Physics, 2018
The off-shell one-loop renormalization of a Higgs effective field theory possessing a scalar potential ∼Φ†Φ−υ22N $$ \sim {\left({\Phi}^{\dagger}\Phi -\frac{\upupsilon^2}{2}\right)}^N $$ with N arbitrary is presented. This is achieved by renormalizing the
Daniele Binosi, Andrea Quadri
doaj   +1 more source

Effective Field Theories

, 2007
Effective field theories encode the predictions of a quantum field theory at low energy. The effective theory has a fairly low ultraviolet cutoff.
T. Kalkreuter, G. Palma, G. Mack, M. Speh   +3 more
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Simplified self-dual electrodynamics

Journal of High Energy Physics
We present a new formulation of self-dual nonlinear electrodynamics in which interactions are determined by an auxiliary-field potential, with causality ensuring a unique solution to the auxiliary-field equation.
Jorge G. Russo, Paul K. Townsend
doaj   +1 more source