Results 151 to 160 of about 1,411,743 (333)
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Nearly critical superfluids in Keldysh-Schwinger formalism
Journal of High Energy PhysicsWe examine the effective theory of critical dynamics near superfluid phase transitions in the framework of the Keldysh-Schwinger formalism. We focus on the sector capturing the dynamics of the complex order parameter and the conserved current ...
Aristomenis Donos, Polydoros Kailidis
doaj +1 more source
Radiative decay of the sub-threshold $1_1^-$ and $2_1^+$ states of $^{16}$O in cluster effective field theory [PDF]
, 2023 Shung-Ichi Ando
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FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Bayesian analysis of muon capture on deuteron in chiral effective field theory [PDF]
, 2023 Alex Gnech, L. E. Marcucci, M. Viviani
openalex +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Weinberg, effective field theories, and time-reversal violation
Nuclear Physics BI offer some glimpses of Steven Weinberg as a mentor, taking as example his influential work on time-reversal violation. I also review some of the implications of this work to low-energy observables using nuclear effective field theories.
U. van Kolck
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Structure of
, 2007 P. Navrátil +4 more
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FEBS Open Bio, EarlyView.Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey +2 more
wiley +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source