Results 61 to 70 of about 13,828,143 (298)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Effective Field Theory for Lattice Nuclei
We show how nuclear effective field theory (EFT) and ab initio nuclear-structure methods can turn input from lattice quantum chromodynamics (LQCD) into predictions for the properties of nuclei. We argue that pionless EFT is the appropriate theory to describe the light nuclei obtained in recent LQCD simulations carried out at pion masses much heavier ...
Barnea, N. +4 more
openaire +6 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Chiral effective field theories for strong and weak dynamics
The chiral effective field theory (ChEFT) is an extension of the chiral perturbation theory that includes the nuclear forces and weak currents at the hadronic and nuclear scales.
Hao Sun, Yi-Ning Wang, Jiang-Hao Yu
doaj +1 more source
Nonperturbative decoupling and effective field theory [PDF]
12 pages no figures.
openaire +3 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Complete CP-eigen bases of meson-baryon chiral lagrangian up to p 5-order
Chiral perturbation theory describes the low energy dynamics of mesons and baryons in terms of the nonlinear Goldstone boson and fermion degrees of freedom. Through the Young tensor technique, we construct the on-shell operator bases for the meson-baryon
Chuan-Qiang Song, Hao Sun, Jiang-Hao Yu
doaj +1 more source
Chern-Simons-matter theories at large baryon number
We study SU(2) Chern-Simons theories at level k coupled to a scalar on T 2 × ℝ at large baryon number. We find a homogeneous but anisotropic ground state configuration for any values of k on the IR fixed-point of those models.
Masataka Watanabe
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source

