Results 81 to 90 of about 13,828,143 (298)

Swampland constraints on 5d N $$ \mathcal{N} $$ = 1 supergravity

Journal of High Energy Physics, 2020
We propose Swampland constraints on consistent 5-dimensional N $$ \mathcal{N} $$ = 1 supergravity theories. We focus on a special class of BPS magnetic monopole strings which arise in gravitational theories.
Sheldon Katz, Hee-Cheol Kim, Houri-Christina Tarazi, Cumrun Vafa   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Relations between anomalous dimensions in the Regge limit

Journal of High Energy Physics
We extend the recent formalism developed for computing rapidity anomalous dimension of form factors using unitarity to the problem of high-energy near forward scattering.
Ira Z. Rothstein, Michael Saavedra
doaj   +1 more source

Effective field theories and cosmological scattering equations

Journal of High Energy Physics, 2022
We propose worldsheet formulae for wavefunction coefficients of the massive non-linear sigma model (NLSM), scalar Dirac-Born-Infeld (DBI), and special Galileon (sGal) theories in de Sitter momentum space in terms of the recently proposed cosmological ...
C. Armstrong, H. Gomez, R. Lipinski Jusinskas, A. Lipstein, J. Mei   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

T T ¯ $$ T\overline{T} $$ -deformation and long range spin chains

Journal of High Energy Physics, 2020
We point out that two classes of deformations of integrable models, developed completely independently, have deep connections and share the same algebraic origin. One class includes the T T ¯ $$ T\overline{T} $$ -deformation of 1+1 dimensional integrable
Balázs Pozsgay, Yunfeng Jiang, Gábor Takács   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Conformal bootstrap at large charge

Journal of High Energy Physics, 2018
We consider unitary CFTs with continuous global symmetries in d > 2. We consider a state created by the lightest operator of large charge Q ≫ 1 and analyze the correlator of two light charged operators in this state.
Daniel Jafferis, Baur Mukhametzhanov, Alexander Zhiboedov   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

QCD effective field theories for heavy quarkonium

, 2006
QCD nonrelativistic effective field theories (NREFT) are the modern and most suitable frame to describe heavy quarkonium properties. Here I summarize few relevant concepts and some of the interesting physical applications (spectrum, decays, production ...
N. Brambilla, Nora Brambilla
core   +1 more source