Results 111 to 120 of about 3,289,970 (333)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Effective field theory for triaxially deformed nuclei
, 2017 Effective field theory (EFT) is generalized to investigate the rotational motion of triaxially deformed even-even nuclei. A Hamiltonian, called the triaxial rotor model (TRM), is obtained up to next-to-leading order (NLO) within the EFT formalism.
Chen, Q. B. +3 more
core +2 more sources
Derivation of effective field theories [PDF]
Physical Review E, 2008 A general self-consistency approach allows a thorough treatment of the corrections to the mean-field approximation (MFA). The natural extension of standard MFA with the help of a cumulant expansion leads to a new point of view on the effective field theories. The proposed approach can be used for a systematic treatment of fluctuation effects of various
openaire +3 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Near-threshold hadron scattering with effective field theory [PDF]
EPJ Web of Conferences. When an exotic hadron locates near the threshold with the channel couplings, the internal structure of the exotic hadron is related to the scattering length. To incorporate the threshold effect, the Flatté amplitude has been often used to determine the
Sone Katsuyoshi, Hyodo Tetsuo
doaj +1 more source
Unitarity problems for an effective field theory description of early universe cosmology. [PDF]
Eur Phys J C Part Fields, 2022 Brandenberger R, Kamali V.
europepmc +1 more source
Neutron Scattering off One-Neutron Halo Nuclei in Halo Effective Field Theory [PDF]
, 2023 Xu Zhang +3 more
openalex +1 more source
, 1998 106 pages, 20 figures. Lectures at the 1997 Les Houches Summer School "Probing the Standard Model of Particle Interactions"
openaire +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source