Results 51 to 60 of about 581,012 (280)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Thermodynamical features of multifragmentation in peripheral Au + Au Collisions at 35 A.MeV

, 1999
The distribution of fragments produced in events involving the multifragmentation of excited sources is studied for peripheral Au + Au reactions at 35 A.MeV. The Quasi-Projectile has been reconstructed from its de-excitation products.
Bonasera, A., Bondorf, J. P., Botvina, A. S., Bougault, R., Bruno, M., D'Agostino, M., Desesquelles, P., Geraci, E., Gulminelli, F., Iori, I., Margagliotti, G. V., Mishustin, I. N., Moroni, A., Neindre, N. Le, Pagano, A., Vannini, G.   +15 more
core   +3 more sources

Integrating testing techniques through process programming [PDF]

, 1989
Integration of multiple testing techniques is required to demonstrate high quality of software. Technique integration has three basic goals: incremental testing capabilities, extensive error detection, and cost-effective application. We are experimenting
Clarke Lori A., D. Richardson, Debra, Debra, L. Osterweil, S. Aha   +5 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Regioselective and stoichiometrically controlled conjugation of photodynamic sensitizers to a HER2 targeting antibody fragment [PDF]

, 2014
The rapidly increasing interest in the synthesis of antibody–drug conjugates as powerful targeted anticancer agents demonstrates the growing appreciation of the power of antibodies and antibody fragments as highly selective targeting moieties.
Boyle, Ross W., Bryden, Francesca, Caddick, Stephen, Chudasama, Vijay, Maruani, Antoine, Savoie, Huguette, Smith, Mark E. B.   +6 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

DNA Sequence Fragment Containing C to A Mutation as a Convenient Mutation Standard for DHPLC Analysis [PDF]

Iranian Journal of Basic Medical Sciences, 2013
Objective(s):  Denaturing high performance liquid chromatography (DHPLC) is a high throughput approach for screening DNA sequence variations. To assess oven calibration, cartridge performance, buffer composition and stability, the WAVE Low and High Range
Hassan Dastsooz, Nazanin Vahedi, Majid Fardaei   +2 more
doaj  

High-resolution melting molecular signatures for rapid identification of human papillomavirus genotypes. [PDF]

PLoS ONE, 2012
BACKGROUND: Genotyping of human papillomarvirus (HPV) is crucial for patient management in a clinical setting. This study accesses the combined use of broad-range real-time PCR and high-resolution melting (HRM) analysis for rapid identification of HPV ...
Ta-Hsien Lee, Tzong-Shoon Wu, Ching-Ping Tseng, Jiantai Timothy Qiu   +3 more
doaj   +1 more source

Quantum fluctuation effects on hyperfragment formation from Xi^- absorption at rest on 12C

, 1998
Formation mechanisms of single, twin, and double hypernuclei from Xi^- absorption at rest on 12C are investigated with an refined microscopic transport model, that incorporates the recently developed Quantal Langevin treatment into Antisymmetrized ...
Akira Ohnishi, Aoki, Aoki, Danielewicz, Danyz, et al., Feldmeier, Fukuda, Gong, Ikeda, Itagaki, Itoh, Jørgen Randrup, Kanada-En'yo, Khaustov, Kiderlen, Lacroix, Lewandowski, Lipkin, Motoba, Nagels, Nakazawa, Nakazawa, Nara, Ohnishi, Ohnishi, Ohnishi, Ohnishi, Ohnishi, Ono, Ono, Ono, Ono, Ono, Prowse, Pühlhofer, Risken, Roche, Schnack, Schnack, Tadokoro, Takemoto, Toru Harada, Volkov, Yamada, Yamada, Yamamoto, Yasushi Nara, Yuichi Hirata   +48 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source