Results 71 to 80 of about 582,070 (278)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

A Novel Approach for Warhead Fragments Velocity Measurement Based on Laser Screen

Journal of Measurement Science and Instrumentation, 2011
The velocity of warhead fragment is key criteria to determine its mutilation efficiency.We have designed an optoelectronic system to accurately measure the average velocity of warhead fragments.The apparatus including two parallel laser screens spaced ...
Ji LIU, Dong-e ZHAO, Han-chang ZHOU
doaj  

OSTEOCHONDRITIS DISSECANS OF THE HIP IN LEGG-CALVÉ-PERTHES DISEASE: CASE REPORT AND REVIEW

Acta Ortopédica Brasileira
Introduction: Legg-Calvé-Perthes disease (LCPD) is the idiopathic osteonecrosis of the capital femoral epiphysis in children. It is a self-healing condition, and the morphology of the hip may vary according to the severity of the disease, among several ...
Luiz Renato Agrizzi de Angeli, Bárbara Lívia Corrêa Serafim, Felippi Guizardi Cordeiro, Felipe Spinelli Bessa, Daniel Augusto Carvalho Maranho   +4 more
doaj   +1 more source

Nucleon Flow and Fragment Flow in Heavy Ion Reactions

, 1993
The collective flow of nucleons and that of fragments in the 12C + 12C reaction below 150 MeV/nucleon are calculated with the antisymmetrized version of molecular dynamics combined with the statistical decay calculation.
A. Ono, A. Ono, A. Ono, A. Volkov, Akira Ono, F. Pühlhofer, F. Sébille, G. D. Westfall, H. Feldmeier, H. Horiuchi, Hisashi Horiuchi, J. Aichelin, J. Dechargé, J. Péter, T. Maruyama, Toshiki Maruyama   +15 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Characteristics of successful expansion of tumor-infiltrating lymphocytes from colorectal cancer liver metastasis

Scientific Reports
Adoptive cell therapy (ACT) utilizing tumor-infiltrating lymphocytes (TILs) has emerged as a successful treatment modality for various malignancies. However, TILs cultured from colorectal cancer (CRC) liver metastasis remain underexplored.
Jina Baek, Gyuheon Choi, GunHee Lee, Hyun Lee, Gyungyub Gong, Hye Seon Park, Chae-Lyul Lim, Joo Young Kim, Hee Jin Lee   +8 more
doaj   +1 more source

Sleeve Fracture of the Patella in Children

Journal of Orthopaedic Surgery, 2008
Purpose. To report the diagnosis, treatment, and outcomes of sleeve patellar fractures in children. Methods. Records of a consecutive series of patients with sleeve patellar fractures were retrospectively reviewed. Results. Of the 11 children (8 boys and
GX Gao, A Mahadev, EH Lee
doaj   +1 more source

Isospin in Reaction Dynamics. The Case of Dissipative Collisions at Fermi Energies

, 2005
A key question in the physics of unstable nuclei is the knowledge of the $EOS$ for asymmetric nuclear matter ($ANM$) away from normal conditions. We recall that the symmetry energy at low densities has important effects on the neutron skin structure ...
M. Di Toro, Via S. Sofia
core   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source