Results 51 to 60 of about 582,070 (278)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Role of Surface Entropy in Statistical Emission of Massive Fragments from Equilibrated Nuclear Systems

, 2002
Statistical fragment emission from excited nuclear systems is studied within the framework of a schematic Fermi-gas model combined with Weisskopf's detailed balance approach.
A.V. Ignatyuk, D.H.E. Gross, D.H.E. Gross, J. B. Natowitz, J. Tõke, J. Tõke, J.B. Elliott, J.B. Natowitz, J.B. Natowitz, J.P. Bondorf, Jan Tõke, Jun Lu, K. Tso, L. Beaulieu, L. Beaulieu, L.G. Moretto, L.G. Moretto, L.G. Moretto, M.E. Fisher, S. Albergo, V.F. Weisskopf, W. Udo Schröder, W.A. Friedman   +22 more
core   +1 more source

Fragmentation of Massive Protostellar Disks [PDF]

, 2006
We examine whether massive-star accretion disks are likely to fragment due to self-gravity. Rapid accretion and high angular momentum push these disks toward fragmentation, whereas viscous heating and the high protostellar luminosity stabilize them.
Adams, Artymowicz, Bally, Bate, Bernard, Beuther, Burkert, Cesaroni, Cesaroni, Chevalier, Chick, Chini, Christopher D. Matzner, De Buizer, De Buizer, De Marchi, Faúndez, Figer, Fleck, Gammie, Gilbert, Goodman, Goodman, Hillenbrand, Hinkley, Kaitlin M. Kratter, Kenyon, Kim, Krumholz, Krumholz, Laughlin, Levin, Matzner, Matzner, McKee, Monnier, Myers, Nelson, Olmi, Palla, Patel, Pinsonneault, Plume, Rafikov, Rice, Semenov, Shakura, Shepherd, Shu, Tan, Tan, Tan, Terebey, Tout, Turner, Van Den Bergh, Webbink, Whitney, Wolfire, Zhang   +59 more
core   +4 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Impact of the amount of parathyroid autotransplantation in total parathyroidectomy for secondary hyperparathyroidism: a prospective randomized trial

Scientific Reports
This prospective randomized study evaluated the effect of the number of transplanted parathyroid fragments on parathyroid hormone (PTH) levels and clinical outcomes in total parathyroidectomy with autotransplantation for secondary hyperparathyroidism ...
Pichit Sittitrai, Danunuch Pasupat, Donyarat Ruenmarkkaew, Hanpon Klibngern, Tapanut Ariyanon, Orapan Sangiamporn, Weerachai Watcharatsiriyuth   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

DNA Sequence Fragment Containing C to A Mutation as a Convenient Mutation Standard for DHPLC Analysis [PDF]

Iranian Journal of Basic Medical Sciences, 2013
Objective(s):  Denaturing high performance liquid chromatography (DHPLC) is a high throughput approach for screening DNA sequence variations. To assess oven calibration, cartridge performance, buffer composition and stability, the WAVE Low and High Range
Hassan Dastsooz, Nazanin Vahedi, Majid Fardaei   +2 more
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Probing the Nuclear Symmetry Energy with Heavy Ion Collisions

, 2010
Heavy Ion Collisions (HIC) represent a unique tool to probe the in-medium nuclear interaction in regions away from saturation. In this report we present a selection of new reaction observables in dissipative collisions particularly sensitive to the ...
Baran, V., Colonna, M., Di Toro, M., Greco, V.   +3 more
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source