Results 101 to 110 of about 2,030 (202)
Advanced Science, EarlyView.This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang +10 more
wiley +1 more source
Diversity and correlation analysis of national bell pepper (Capsicum annuum L.) accessions in Niger
Рослинництво та ґрунтознавствоThe study on the diversity and correlation analysis of national bell pepper accessions is of paramount importance because it documented and conserved valuable local genetic resources while providing essential information for breeding and varietal ...
H.O. Maiga +3 more
doaj +1 more source
, 2022 Paljude kalaliikide arvukuse vähenemine näitab kiiret vajadust rakendada informatiivsemaid seireprogramme ning parandada käimasolevate majandamis- ja kaitsemeetmete tõhusust (Rice & Legace 2007). Alates 1960-ndatest aastatest on magevees ja vooluveekogudes elavate kalaliikide seire kõige laialdasemalt kasutatavateks vahenditeks nakkevõrgud ja ...
Vasemägi, Anti +8 more
openaire +1 more source
Advanced Science, EarlyView.In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu +13 more
wiley +1 more source
A Conserved DT2‐bZIP66‐NF‐YC4 Regulatory Module Confers Drought Tolerance in Rice and Arabidopsis
Advanced Science, EarlyView.This study identifies a conserved tripartiteDT2–bZIP66–NF‐YC4 transcriptional module that enhances rice drought tolerance by activating stress‐responsive genes. This regulatory complex is functionally conserved across cereals and Arabidopsis, providing promising targets for engineering drought‐resilient crops. ABSTRACT Drought stress severely restricts
Jun Shen +18 more
wiley +1 more source
Advanced Science, EarlyView.Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes +15 more
wiley +1 more source
Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing
Advanced Science, EarlyView.A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo +11 more
wiley +1 more source
A small-scale assessment of the availability of EURISCO accessions
Genetic ResourcesA critical assessment of plant genetic resource (PGR) availability in Europe reveals a significant gap between documented accessions and those that are practically obtainable for researchers and breeders.
Erik Wijnker, Theo van Hintum
doaj +1 more source
The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton
Advanced Science, EarlyView.Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang +32 more
wiley +1 more source
AnimalsThe historical increase in the occurrence of extreme weather events in Spain during the last thirty years makes it a perfect location for the evaluation of climate change.
Carmen Marín Navas +5 more
doaj +1 more source