Results 171 to 180 of about 2,030 (202)

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

Advanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li, Joanne T. M. Tan, Lei Xiang, Jiandi Liu, Ayla Hoogendoorn, Victoria A. Nankivell, Lauren Sandeman, Richard Le, Rouyan Chen, Robert A. McLaughlin, Peter J. Psaltis, Johan W. Verjans, Christina A. Bursill   +12 more
wiley   +1 more source

Hemp Cultivation and Crop Diversification: Implications for Ecosystem Services in Kentucky

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study examines the ecosystem benefits of expanding hemp cultivation by assessing its impact on crop diversity. Using scenario‐based simulations and fixed‐effect panel regressions with county‐level data in Kentucky, we find that increased hemp acreage tends to enhance crop diversity, improving water quality and bird diversity.
Yunsun Park, Seong D. Yun, Brandy E. Phipps, Tyler Mark, Craig Schluttenhofer   +4 more
wiley   +1 more source

Farmers' Preferences for Gene Editing Crops and Influencing Factors

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Gene editing (GE) is gaining momentum worldwide, but limited data on UK farmers' preferences hinders our understanding of its potential impact amid deregulation debates. Based on a survey of 200 English arable farmers, we employ a Latent Class Analysis and Multinomial Logit regressions to investigate current preferences for GE crops.
Bertolozzi‐Caredio Daniele, Vigani Mauro   +1 more
wiley   +1 more source

Correction to Effective number of white shark ( Carcharodon carcharias , Linnaeus) breeders is stable over four successive years in the population adjacent to eastern Australia and New Zealand

Ecology and Evolution
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Effective number of breeders provides a link between interannual variation in stream flow and individual reproductive contribution in a stream salmonid

Molecular Ecology, 2015
AbstractThe effective number of breeders that give rise to a cohort (Nb) is a promising metric for genetic monitoring of species with overlapping generations; however, more work is needed to understand factors that contribute to variation in this measure in natural populations.
Andrew Whiteley, Matthew O'Donnell
exaly   +4 more sources

Interannual variation in effective number of breeders and estimation of effective population size in long‐lived iteroparous lake sturgeon (Acipenser fulvescens)

Molecular Ecology, 2013
AbstractQuantifying interannual variation in effective adult breeding number (Nb) and relationships between Nb, effective population size (Ne), adult census size (N) and population demographic characteristics are important to predict genetic changes in populations of conservation concern.
Patrick Forsythe, Kim T Scribner
exaly   +4 more sources

Using factorial mating designs to increase the effective number of breeders in fish hatcheries

Aquaculture, 2007
Abstract We used Monte Carlo simulations to evaluate the potential of full- and partial-factorial mating designs to increase the effective number of breeders in fish hatchery operations, using two probability distributions (normal and uniform) to generate individual fitness values, two methods (multiplicative and additive) of combining fitness values
C. Busack, C. Knudsen
exaly   +3 more sources

The impact of repeat spawning of males on effective number of breeders in hatchery operations

Aquaculture, 2007
In conservation hatcheries, typically a great emphasis is placed on maximizing the effective number of breeders through spawning an appropriate number of spawners, spawning equal numbers of males and females when possible, and by mating either in a single-pair or factorial fashion.
C. Busack
exaly   +3 more sources

Reduced Genetic Variation and Decreased Effective Number of Breeders in Five Year-Classes of Cultured Geoducks (Panopea generosa)

Journal of Shellfish Research, 2015
ABSTRACT Aquaculture for the Pacific geoduck (Panopea generosa) is a small but expanding industry in Washington state, where geoducks are native and genetic interactions between wild and cultured geoducks are likely. To examine the potential genetic implications of geoduck aquaculture, genetic diversity, and effective number of breeders (Nb), five ...
Brent Vadopalas, Carolyn S Friedman
exaly   +3 more sources