Results 21 to 30 of about 96,311 (241)

New positron emission radiopharmaceuticals in urological radionuclide imaging

open access: yesPočki, 2019
The literature review examines the historical aspects and key issues of the clinical application of new radiopharmaceuticals (RF) for positron emission tomography (PET).
P.A. Korol, O.V. Shcherbina
doaj   +1 more source

Conventional Pig as Animal Model for Human Renal Drug Excretion Processes: Unravelling the Porcine Renal Function by Use of a Cocktail of Exogenous Markers

open access: yesFrontiers in Pharmacology, 2020
Over recent years, pigs have been promoted as potential animal model due to their anatomical and physiological similarities with humans. However, information about the contribution of distinct renal elimination processes [glomerular filtration rate (GFR),
Laura Dhondt   +16 more
doaj   +1 more source

Renal hyperfiltration and systemic blood pressure in patients with uncomplicated type 1 diabetes mellitus. [PDF]

open access: yesPLoS ONE, 2013
Patients with type 1 diabetes mellitus (DM) and renal hyperfiltration also exhibit systemic microvascular abnormalities, including endothelial dysfunction. The effect of renal hyperfiltration on systemic blood pressure (BP) is less clear.
Gary K Yang   +3 more
doaj   +1 more source

Endothelial mineralocorticoid receptor ablation does not alter blood pressure, kidney function or renal vessel contractility. [PDF]

open access: yesPLoS ONE, 2018
Aldosterone blockade confers substantial cardiovascular and renal protection. The effects of aldosterone on mineralocorticoid receptors (MR) expressed in endothelial cells (EC) within the renal vasculature have not been delineated.
Sidsel B Laursen   +5 more
doaj   +1 more source

QiShenYiQi Pills, a Compound Chinese Medicine, Prevented Cisplatin Induced Acute Kidney Injury via Regulating Mitochondrial Function

open access: yesFrontiers in Physiology, 2017
Nephrotoxicity is a serious adverse effect of cisplatin chemotherapy that limits its clinical application, to deal with which no effective management is available so far.
Li Zhou   +41 more
doaj   +1 more source

Renal clearance of heparin-binding protein and elimination during renal replacement therapy: Studies in ICU patients and healthy volunteers.

open access: yesPLoS ONE, 2019
BackgroundHeparin-binding protein (HBP) is released by neutrophils upon activation, and elevated plasma levels are seen in inflammatory states like sepsis, shock, cardiac arrest, and burns. However, little is known about the elimination of HBP. We wanted
Line Samuelsson   +7 more
doaj   +1 more source

Association of ABCB1 genetic variants with renal function in Africans and in Caucasians

open access: yesBMC Medical Genomics, 2008
Background The P-glycoprotein, encoded by the ABCB1 gene, is expressed in human endothelial and mesangial cells, which contribute to control renal plasma flow and glomerular filtration rate.
Elston Robert C   +12 more
doaj   +1 more source

Protective effect of selenium on cisplatin induced nephrotoxicity: A double-blind controlled randomized clinical trial [PDF]

open access: yesJournal of Nephropathology, 2013
Background: Renal injury is common following cisplatin infusion. Some agents have been used to attenuate cisplatin nephrotoxicity. However, except hydration, none of them has been proved to be effective.
Ali Ghorbani, Bita Omidvar, Abazar Parsi
doaj   +1 more source

The effect of nisoldipine on apparent liver blood flow and effective renal plasma flow. [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 1985
The effects of the acute and continued administration of the calcium antagonist nisoldipine on hepatic and renal blood flow and on renal function were studied in nine normotensive volunteers. There were no significant changes in supine blood pressure or heart rate but acute administration significantly increased both apparent liver blood flow and ...
MEREDITH PA   +3 more
openaire   +3 more sources

Functional assessment of renal damage in children with primary vesicoureteral reflux

open access: yesFrontiers in Pediatrics
ObjectivesTo evaluate the renal function damage in children with primary vesicoureteral reflux (VUR).MethodsA total of 226 children with VUR (65 cases with left, 39 with right, and 122 cases with bilateral VUR) were screened.
Yaju Zhu, Yufeng Li, Jing Jin, Jiajia Ni
doaj   +1 more source

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