Results 101 to 110 of about 5,815,781 (251)

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Secrecy and Throughput Performance of Cooperative Cognitive Decode-and-Forward Relaying Vehicular Networks with Direct Links and Poisson Distributed Eavesdroppers

Cooperative communication and cognitive radio can effectively improve spectrum utilization, coverage range, and system throughput of vehicular networks, whereas they also incur several security issues and wiretapping attacks.
Jianli Xie, Cuiran Li, Shaoyi Du, Lin Su, Yadan Liu, Fan Wang   +5 more
core   +1 more source

Swiss Banking Secrecy; The Erosion of an Institution. IES WORKING PAPER 2/2008 [PDF]

, 2008
Switzerland has for a long time been an important centre of banking services in Europe and beyond. Consequently, the banking sector has become important to Switzerland’s prosperity. This paper focuses on a central reason behind the success of the Swiss
Lamensch, Marie
core  

Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring

Advanced Science, EarlyView.
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen, Weiyi Wang, Yang Wang, Yiqiang Wu, Xiaohong Liu, Wei Zhang, Juanjuan Ou   +6 more
wiley   +1 more source

A Federated Learning Scheme for Eavesdropper Detection in B5G - IIoT Network Orientations

IEEE Open Journal of the Communications Society
In heterogeneous Beyond 5G (B5G) environments, the adoption of sophisticated Physical Layer (PHY) enhancements, such as Physical Layer Security (PLS) techniques, play a vital role in safeguarding sensitive transmissions against eavesdropping threats ...
Maria Lamprini A. Bartsioka, Ioannis A. Bartsiokas, Panagiotis K. Gkonis, Anastasios K. Papazafeiropoulos, Dimitra-Theodora I. Kaklamani, Iakovos S. Venieris   +5 more
doaj   +1 more source

The Protection of Innovations [PDF]

This paper proposes a model where firms invest in secrecy to limit technological spillovers accruing to their competitors, in addition to investing in cost-reducing R&D.
Gamal Atallah
core  

Throughput maximization in multi-hop wireless networks under a secrecy constraint

, 2016
This paper analyzes the achievable throughput of multi-hop sensor networks for industrial applications under a secrecy constraint and malicious jamming. The evaluation scenario comprises sensors that measure some relevant information of the plant that is
Alves, Hirley, Latva-aho, Matti, de Lima, Carlos H.M. [UNESP], Nardelli, Pedro H.J., de Lima, Carlos H.M.   +4 more
core   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

Secrecy in Untrusted Networks

, 2003
We investigate the protection of migrating agents against the untrusted sites they traverse. The resulting calculus provides a formal framework to reason about protection policies and security protocols over distributed, mobile infrastructures, and aims ...
Bugliesi, M., Crafa, S., Prelic, A., Sassone, V.   +3 more
core   +2 more sources

Multi‐Dimensional Physical‐Layer Security via Digitally Mediated Space–Time Modulation

Advanced Science, EarlyView.
Digitally mediated space–time modulation moves radiation control beyond hardware‐bound switching. Multiple information‐bearing and masking waveforms are jointly synthesized at baseband and coherently coupled to simple periodic time modulation, enabling programmable, independently directed multi‐beam radiation without increasing switching‐state ...
Kejin Chen, Heng Mao, Feng Yang, Gengbo Wu, Lei Zhang, Yikai Chen, Shi‐Wei Qu, Jun Hu, Shiwen Yang   +8 more
wiley   +1 more source