Results 71 to 80 of about 1,350,701 (268)

The Effects of Muscle Stress on Oxidative Stress

open access: yesRigakuryoho Kagaku, 2006
異なる筋収縮様式(等張性負荷と等尺性負荷)による筋力負荷が酸化ストレス度に及ぼす影響について,健康成人31例(平均22.9±3.4歳)で検討した。酸化ストレス度は活性酸素・フリーラジカル分析装置を使用し,安静時と負荷終了直後の計2回指尖より採血し,hydroperoxide濃度を光学計測法により計測した。筋力負荷はJAMARハンドダイナモメータを用いて,右手に対して等張性負荷と等尺性負荷によるハンドグリップ運動を実施した。その結果,酸化ストレス度は,等尺性と等張性負荷共に安静時と負荷後を比較すると有意差を認めなかった。一方,血圧や心拍数は,等尺性と等張性負荷共に負荷中では,安静時と比較すると有意な増加を認めた(いずれもp<.001)。このことから,等尺性と等張性負荷共に血圧や心拍数の増加があっても ...
Hiroshi MARUOKA   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Relations and Links Between Soil Mechanics, Porous Media Physics, Physiochemical Theory, and Effective Medium Theory

open access: yesFrontiers in Physics, 2019
Modern soil mechanics (geotechnical engineering) was developed as a branch of civil engineering from the 1920's. While modern porous media physics was developed as a branch of physics and applied mathematics from roughly the same period of time.
Gustav Grimstad   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Stress-Based Model for Interpreting Shear Wave Velocity from Seismic Cone Penetration Tests in Unsaturated Soil

open access: yesGeosciences
Shear wave velocity is an important parameter for estimating soil properties used in analyzing the dynamic response of soil to seismic loading. This paper focuses on developing a model for predicting shear wave velocity in unsaturated soils.
Tareq Abuawad   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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