Results 91 to 100 of about 1,388,982 (268)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

STRESS DRIVEN INTERFACE DYNAMICS: THE EFFECTS OF SURFACE STRESS

International Journal of Bifurcation and Chaos, 2007
We study the effects of surface stress on the dynamics of a solid interface which evolves by surface diffusion. In the absence of surface stress, it is known that a flat interface is unstable for long wavelength perturbations and that in the nonlinear regime this instability develops into the formation of a sharp cusp.
openaire   +5 more sources

Permeability model of matrix-damaged and fractured coal under coupled effects of effective stress, temperature, and moisture

Meitan kexue jishu
The permeability of coal seams in China is generally low. Meanwhile, during the coal seam mining process, the permeability is also affected by the coupling of effective stress, temperature and moisture.
Shouqing LU, Jiaojing ZONG, Yujin QIN, Zhanyou SA, Jie LIU, Rong ZHANG   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Perceived stress and renewal: The effects of long-term stress on the renewal effect

Neurobiology of Learning and Memory
Two online experiments evaluated the relationship between long-term stress, as measured with the PerceivedStress Scale-10, and the Renewal Effect. In the first experiment renewal was assessed with a behavioral suppressiontask in a science-fiction based video game.
Borja Nevado, James Byron Nelson
openaire   +2 more sources

Experimental study of oil matrix and fracture flow capacity of shale oil in Subei Basin

Youqicang pingjia yu kaifa
Shale oil reservoirs present complex pore structures and ultra-low permeability, making the evaluation of flow capacity in both the reservoir matrix and various fracture types after fracturing crucial for developing effective work systems. In this study,
DUAN Hongliang, SHEN Tingshan, SUN Jing, HONG Yafei, LI Sichen, LU Xianrong, ZHANG Zhengyang   +6 more
doaj  

Comparative analysis of coal permeability models accounting for the stress-strain state of the rock mass

Горные науки и технологии
Coal seam permeability is a key parameter controlling degassing efficiency, the intensity of methane emission, and the safety of mining operations. As permeability decreases with depth and is critically dependent on the stress-strain state, its reliable ...
A. I. Manevich, K. S. Kolikov, N. V. Ledyaev, I. V. Losev, D. Zh. Akmatov, R. V. Shevchuk   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source