Results 91 to 100 of about 1,350,701 (268)

STRESS DRIVEN INTERFACE DYNAMICS: THE EFFECTS OF SURFACE STRESS

International Journal of Bifurcation and Chaos, 2007
We study the effects of surface stress on the dynamics of a solid interface which evolves by surface diffusion. In the absence of surface stress, it is known that a flat interface is unstable for long wavelength perturbations and that in the nonlinear regime this instability develops into the formation of a sharp cusp.
openaire   +5 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Perceived stress and renewal: The effects of long-term stress on the renewal effect

Neurobiology of Learning and Memory
Two online experiments evaluated the relationship between long-term stress, as measured with the PerceivedStress Scale-10, and the Renewal Effect. In the first experiment renewal was assessed with a behavioral suppressiontask in a science-fiction based video game.
Borja Nevado, James Byron Nelson
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Permeability model of matrix-damaged and fractured coal under coupled effects of effective stress, temperature, and moisture

Meitan kexue jishu
The permeability of coal seams in China is generally low. Meanwhile, during the coal seam mining process, the permeability is also affected by the coupling of effective stress, temperature and moisture.
Shouqing LU, Jiaojing ZONG, Yujin QIN, Zhanyou SA, Jie LIU, Rong ZHANG   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Experimental study on the permeability features of long flame gas water phase

Gong-kuang zidonghua
There is a large amount of CBM in the long flame coal. With the continuous increase of mining depth, it is necessary to explore the complex permeability features between CBM and groundwater in the coal reservoir to reduce the difficulty of CBM mining and
CHEN Gonghui, TANG Mingyun, NING Jiangqi, ZHANG Hailu   +3 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Initial effective stress controls the nature of earthquakes. [PDF]

Nat Commun, 2020
Passelègue FX, Almakari M, Dublanchet P, Barras F, Fortin J, Violay M.   +5 more
europepmc   +1 more source