Results 101 to 110 of about 1,350,701 (268)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Study on the influencing factors of radial non-Darcy seepage of gas in CO2 fracturing boreholes

open access: yesMeitan xuebao
CO2 fracturing, as a key technology to improve the gas extraction efficiency of low-permeability coal seams, has a core mechanism of injecting high-pressure CO2 into coal seams to induce the generation of a fracture network within the coal body, thus ...
Tianjun ZHANG   +6 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Pore Pressure Prediction and Fluid Contact Determination: A Case Study of the Cretaceous Sediments in the Bredasdorp Basin, South Africa

open access: yesApplied Sciences
Pore pressure prediction gives drillers an early warning of potential oil and gas kicks, enabling them to adjust mud weight pre-emptively. A kick causes a delay in drilling practices, blowouts, and jeopardization of the wells.
Phethile Promise Shabangu   +2 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Experimental study of oil matrix and fracture flow capacity of shale oil in Subei Basin

open access: yesYouqicang pingjia yu kaifa
Shale oil reservoirs present complex pore structures and ultra-low permeability, making the evaluation of flow capacity in both the reservoir matrix and various fracture types after fracturing crucial for developing effective work systems. In this study,
DUAN Hongliang   +6 more
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Research Progress of Effective Stress and Effective Stress Equation [PDF]

open access: yesCurrent Trends in Civil & Structural Engineering, 2021
openaire   +1 more source

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