Results 61 to 70 of about 7,143,220 (301)

Threshold Determination for Effective Water Injection in Coal Seams: Insights from Numerical Simulation

open access: yesApplied Sciences
Coal seam water injection is the most basic and effective dust control technology used on the coal mining face. Numerical simulations are helpful for predicting the humidity range of coal seam water injection.
Lei Liu, Gun Huang, Yunfei Zhao
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Estimating the time-varying effective reproduction number via Cycle Threshold-based Transformer.

open access: yesPLoS Computational Biology
Monitoring the spread of infectious disease is essential to design and adjust the interventions timely for the prevention of the epidemic outbreak and safeguarding the public health.
Xin-Yu Zhang   +6 more
doaj   +1 more source

Informing HPV vaccine pricing for government-funded vaccination in mainland China: a modelling studyResearch in context

open access: yesThe Lancet Regional Health. Western Pacific
Summary: Background: The high price of HPV vaccines remains a significant barrier to vaccine accessibility in China, hindering the country’s efforts toward cervical cancer elimination and exacerbating health inequity.
Tingting You   +9 more
doaj   +1 more source

Effects of temperatures on the development and reproduction of the armyworm, Mythimna roseilinea: Analysis using an age-stage, two-sex life table

open access: yesJournal of Integrative Agriculture, 2018
The armyworm Mythimna roseilinea (Walker) is a major pest of grain crops in South China. So far little is known about its basic biology and ecology, making prediction of population dynamics difficult.
Jian-yang QIN   +5 more
doaj   +1 more source

Atherosclerotic cardiovascular disease thresholds for statin initiation among people living with HIV in Thailand: A cost-effectiveness analysis.

open access: yesPLoS ONE, 2021
BackgroundPeople living with HIV (PLHIV) have an elevated risk of atherosclerotic cardiovascular disease (ASCVD) compared to their uninfected peers. Expanding statin use may help alleviate this burden.
David C Boettiger   +7 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Effects of threshold resummation for large-x PDF in large momentum effective theory

open access: yesJournal of High Energy Physics
Parton distribution functions (PDFs) at large x are challenging to extract from experimental data, yet they are essential for understanding hadron structure and searching for new physics beyond the Standard Model.
Xiangdong Ji   +3 more
doaj   +1 more source

NELD-EC: Neighborhood-Effective-Line-Density-Based Euclidean Clustering for Point Cloud Segmentation

open access: yesSensors
For the problem that it is difficult to effectively cluster lidar point clouds with irregular shapes and uneven densities, a Neighborhood Effective Line Density (NELD)-based Euclidean Clustering (NELD-EC) algorithm is proposed in this paper.
Zhigang Su   +5 more
doaj   +1 more source

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