Results 81 to 90 of about 7,143,220 (301)
Divergence coding for convolutional codes
MATEC Web of Conferences, 2017 In the paper we propose a new coding/decoding on the divergence principle. A new divergent multithreshold decoder (MTD) for convolutional self-orthogonal codes contains two threshold elements.
Valery Zolotarev +4 more
doaj +1 more source
The Effect of Myopia on Contrast Thresholds
Investigative Opthalmology & Visual Science, 2007 To examine the relationship between the degree of myopia and foveally measured contrast thresholds.Monocular thresholds for positive and negative contrast were obtained from 60 myopes (-1.0 to -8.0 D) and 20 emmetropes of similar age. The contrast thresholds were measured at different background luminance levels, photopic and mesopic, by using a visual
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Threshold concept knowledge in analogue electronics: Support and assessment [PDF]
, 2012 In electrical engineering, as in other academic disciplines, there exist special, threshold concepts, where students often get stuck but which once grasped reveal new ways of thinking about a subject.
Scott, Jonathan B. +2 more
core
Learning from the Prevention and Early Intervention Initiative in Ireland [PDF]
, 2016 Centre for Effective Services (CES)
core +6 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Discover Applied SciencesMetal pollution in the sediment of the River Ganga emerged as a severe concern over decades, where the middle stretch at Patna has been poorly studied.
Mohammed Aasif Sulaiman +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source