Results 91 to 100 of about 2,662,524 (294)

Effective mass signatures in multiphoton pair production

open access: yes, 2014
Electron-positron pair production in oscillating electric fields is investigated in the nonperturbative threshold regime. Accurate numerical solutions of quantum kinetic theory for corresponding observables are presented and analyzed in terms of a ...
Alkofer, Reinhard   +2 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Top Pair Production at Threshold and Effective Theories

open access: yes, 2003
I give an introduction to the effective field theory description of top pair production at threshold in e+e- annihilation. The impact of the summation of logarithms of the top quark velocity including most recent results at next-to-next-to-leading ...
Hoang, A. H.
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Impact of fast sodium channel inactivation on spike threshold dynamics and synaptic integration.

open access: yesPLoS Computational Biology, 2011
Neurons spike when their membrane potential exceeds a threshold value. In central neurons, the spike threshold is not constant but depends on the stimulation. Thus, input-output properties of neurons depend both on the effect of presynaptic spikes on the
Jonathan Platkiewicz, Romain Brette
doaj   +1 more source

Lack of analgesic efficacy in female rats of\ud the commonly recommended oral dose of\ud buprenorphine [PDF]

open access: yes, 2006
Previous work in our laboratory showed that the recommended oral dose of buprenorphine (0.5 mg/kg) was not as effective\ud as the standard therapeutic subcutaneous dose for postoperative analgesia in male Long-Evans (hooded) and Sprague-Dawley (albino ...
DiPirro, Dr. Jean M.   +4 more
core  

Dynamical Threshold Enhancement and Resummation in Drell-Yan Production

open access: yes, 2008
Partonic cross sections for the production of massive objects in hadronic collisions receive large corrections when the invariant mass of the initial-state partons is just above the production threshold.
Becher, Thomas   +2 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Effective Theory Approach to W-Pair Production near Threshold

open access: yes, 2007
In this talk, I review the effective theory approach to unstable particle production and present results of a calculation of the process e- e+ ->mu- nubar_mu u dbar X near the W-pair production threshold up to next-to-leading order in GammaW/MW ~ alpha ~
Schwinn, Christian
core  

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