Results 101 to 110 of about 7,143,220 (301)

Temperature-dependent development, predation, and life table of Sphaerophoria macrogaster (Thomson) (Diptera: Syrphidae) feeding on Myzus persicae (Sulzer) (Homoptera: Aphididae)

open access: yesOpen Life Sciences
Sphaerophoria macrogaster (Thomson) (Diptera: Syrphidae) is an important predator of Myzus persicae (Sulzer) (Homoptera: Aphididae). In this study, the morphological characteristics and living habits of S. macrogaster were observed and recorded.
Fan Jijun   +8 more
doaj   +1 more source

Effect of pre-existing damage on delamination growth in repeatedly indented composites

open access: yesMaterials & Design
Improvements in current design approaches require further studies of the damage interaction effects of composite materials subjected to repeated out-of-plane concentrated loads.
L. Huo   +2 more
doaj   +1 more source

Evidence That There are Threshold Effects in Risk of Radiation. [PDF]

open access: yesJournal of Nuclear Science and Technology, 1998
This review provides evidence that thresholds are observd in atomic bomb survivors for teratogenic and genetic effects of radiation and that for rodents subjected to radon gas and tritiated drinking water, radiation becomes non-carcinogenic at low dose-rates.
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Effects of Parcellation and Threshold on Brain Connectivity Measures

open access: yesPLOS ONE, 2019
Abstract It is shown that the statistical properties of connections between regions of the brain and their dependence on coarse-graining and thresholding in published data can be reproduced by a simple distance-based physical connectivity model.
T. C. Lacy, P. A. Robinson
openaire   +4 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Impact of fast sodium channel inactivation on spike threshold dynamics and synaptic integration.

open access: yesPLoS Computational Biology, 2011
Neurons spike when their membrane potential exceeds a threshold value. In central neurons, the spike threshold is not constant but depends on the stimulation. Thus, input-output properties of neurons depend both on the effect of presynaptic spikes on the
Jonathan Platkiewicz, Romain Brette
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Clinical study on effective negative pressure threshold of skin flap drainage after breast cancer surgery

open access: yesHuli yanjiu, 2016
Objective:To probed into the effective negative pressure threshold of skin flap drainage after breast cancer surgery.Methods:A total of 360 patients placed the skin flap drainage after breast modified radical surgery were randomly divided into -20 kPa ...
韩玲, 王蓓, 王开慧, 潘俊
doaj  

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