Results 241 to 250 of about 8,190,661 (311)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

School Quality and Effectiveness [PDF]

Arnaud Chevalier, Peter Dolton, Ros Levacic   +2 more
core  

Unlocking Value: A Cost-Effectiveness Analysis of Hip PJI Diagnostic Pathways Employing the European Bone and Joint Infection Society/Musculoskeletal Infection Society Definition. [PDF]

Arthroplast Today
Diaz-Ledezma C, Zedan AM, Xiao A, Barber T.   +3 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Nirsevimab effectiveness, number needed to immunize and impact on severe RSV outcomes, a test-negative study in Quebec, Canada. [PDF]

Lancet Reg Health Am
Carazo S, Ouakki M, Skowronski DM, Paquette M, Brousseau N, Talbot D, Guay CA, Quach C, Gilca R, Papenburg J.   +9 more
europepmc   +1 more source

Cost-effectiveness analysis of the use of faricimab in diabetic macular edema in China. [PDF]

J Comp Eff Res
Shi F, Tan S, Shu Y, Liu T, Xia Y, Buehrer C, Han S.   +6 more
europepmc   +1 more source

Economic evaluation of anti-malarial drug policies across presidential regimes in Nigeria: A comparative analysis from 1999 to present. [PDF]

PLoS One
Elendu C.
europepmc   +1 more source

Optimal cervical cancer screening strategies for unvaccinated and HPV-vaccinated cohorts in the United States: a comprehensive comparative modeling analysis. [PDF]

Lancet Reg Health Am
de Bondt DD, Simms KT, Naslazi E, Killen J, Kim JJ, Hontelez JAC, Burger EA, Regan MC, Smith MA, Sy S, Canfell K, de Kok IMCM.   +11 more
europepmc   +1 more source