Results 261 to 270 of about 5,703,320 (311)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Reassessing ¹⁷⁷Lu-PSMA-617 Acquisition Costs: Implications for U.S. Radiopharmaceutical Therapy Cost-Effectiveness Analyses. [PDF]

J Nucl Med
Flannery K, Cavanaugh PF, Steele K.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

HIV pre-exposure prophylaxis in US prison settings: a model-based cost-effectiveness study. [PDF]

Lancet Reg Health Am
Park Y, Goldhaber-Fiebert JD, Cipriano LE.   +2 more
europepmc   +1 more source

Implementing Culturally Tailored Diabetes Prevention in Hispanic Communities: An Integrative Review Using the RE-AIM Framework. [PDF]

Prev Chronic Dis
Nguyen R.
europepmc   +1 more source

Comment on Värendh et al. A Cost-Effectiveness Analysis of the Sentio Bone Conduction Hearing Implant System in the Australian Healthcare Setting. <i>J. Mark. Access Health Policy</i> 2026, <i>14</i>, 8. [PDF]

J Mark Access Health Policy
Brunner M.
europepmc   +1 more source

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The effect of effects on effectiveness: A boon-bane asymmetry

Cognition, 2020
Beliefs about how effective a cause will be at achieving possible outcomes are critical inputs into a range of decisions, from how to treat an illness to which products to purchase. We identify scope-the number of distinct outcomes a cause is known to achieve-as an important input into judgments of efficacy.
Abigail B, Sussman, Daniel M, Oppenheimer   +1 more
openaire   +2 more sources

The Bohr Effect and the Haldane Effect

Scandinavian Journal of Clinical and Laboratory Investigation, 1973
(1973). The Bohr Effect and the Haldane Effect. Scandinavian Journal of Clinical and Laboratory Investigation: Vol. 31, No. 1, pp. 1-8.
O, Siggaard-Andersen, L, Garby
openaire   +2 more sources

Effective Measures of ''Effective Discharge''

World Environmental and Water Resources Congress 2008, 2008
Abstract The concept of effective discharge, Qe, was introduced by Wolman and Miller (1960) as that stream discharge that transports the most sediment over time. Recently, the validity of Qe as an overall descriptor of sediment transport has been questioned because of its various interpretations and methods of calculation.
Lauren Klonsky, Richard M. Vogel
openaire   +1 more source