Results 201 to 210 of about 62,761 (235)
Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare
Advanced Robotics Research, EarlyView.Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin +3 more
wiley +1 more source
Advanced Science, EarlyView.In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu +7 more
wiley +1 more source
ESCRT: A Cellular Nexus of Plant Immunity and Pathogen Counter-Strategies. [PDF]
Mol Plant PatholSexton WK, Xiao S.
europepmc +1 more source
Annual Review of Immunology, 2023 The innate immune system detects pathogens via germline-encoded receptors that bind to conserved pathogen ligands called pathogen-associated molecular patterns (PAMPs). Here we consider an additional strategy of pathogen sensing called effector-triggered immunity (ETI).
Russell Vance, Moritz Gaidt
exaly +3 more sources
Guardians of the Cell: Effector-Triggered Immunity Steers Mammalian Immune Defense [PDF]
Trends in Immunology, 2019 The mammalian innate immune system deals with invading pathogens and stress by activating pattern-recognition receptors (PRRs) in the host. Initially proposed to be triggered by the discrimination of defined molecular signatures from pathogens rather than from self, it is now clear that PRRs can also be activated by endogenous ligands, bacterial ...
Emma Creagh +2 more
exaly +5 more sources
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Effector-triggered immunity in mammalian antiviral defense
Trends in Immunology, 2022Effector-triggered immunity (ETI) is a common defense strategy used by mammalian host cells that is engaged upon detection of the enzymatic activities of pathogen-encoded proteins or the effects of their expression on cellular homeostasis. However, in contrast to the effector-triggered responses engaged upon bacterial infection, much less is understood
Megan H. Orzalli, Pooja Parameswaran
openaire +2 more sources
A Brief Introduction to Effector-Triggered Immunity
2022Detection of microbes by the host is essential to restrict microbial colonization, to clear pathogens, and to mount adapted defense reactions, and thus is the key function of the innate immune systems of plants and mammals. Here we provide an introduction into pathogen recognition by the innate immune system of both plants and animals.
Thomas A, Kufer +1 more
openaire +2 more sources
Immunity to Rice Blast Disease by Suppression of Effector-Triggered Necrosis [PDF]
Current Biology, 2016 Hemibiotrophic pathogens are some of the most destructive plant pathogens, causing huge economic losses and threatening global food security. Infection with these organisms often involves an initial biotrophic infection phase, during which the pathogen spreads in host tissue asymptomatically, followed by a necrotrophic phase, during which host-cell ...
Guo-Liang Wang +2 more
exaly +3 more sources
NLRs guard metabolism to coordinate pattern- and effector-triggered immunity
Nature, 2021Pattern-triggered immunity (PTI) and effector-triggered immunity (ETI) in plants enable them to respond to pathogens by activating the production of defence metabolites that orchestrate immune responses1-4. How the production of defence metabolites is promoted by immune receptors and coordinated with broad-spectrum resistance remains elusive.
Keran Zhai +19 more
openaire +2 more sources
Effector-triggered immunity by the plant pathogen Phytophthora
Trends in Microbiology, 2006A new genetic locus mediating avirulence in the potato late blight pathogen Phytophthora infestans has been discovered. The Avr3b-Avr10-Avr11 locus is recognized by three different potato resistance genes, and is different from other Avr loci that have been identified thus far.
Dinah, Qutob +2 more
openaire +2 more sources