Results 91 to 100 of about 747,789 (299)

Discovery of Three Bemisia tabaci Effectors and Their Effect on Gene Expression in Planta

Molecular Plant-Microbe Interactions
Bemisia tabaci (whitefly) is a polyphagous agroeconomic pest species complex. Two members of this species complex, Mediterranean (MED) and Middle-East-Asia Minor 1 (MEAM1), have a worldwide distribution and have been shown to manipulate plant defenses ...
Paula J. M. van Kleeff, Marieke Mastop, Pulu Sun, Sarmina Dangol, Eva van Doore, Henk L. Dekker, Gertjan Kramer, Soohyun Lee, Choong-Min Ryu, Martin de Vos, Robert C. Schuurink   +10 more
doaj   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

GEF-effector interactions [PDF]

Cellular Logistics, 2014
Members of the Arf family of small GTP-binding proteins, or GTPases, are activated by guanine nucleotide exchange factors (GEFs) that catalyze GDP release from their substrate Arf, allowing GTP to bind. In the secretory pathway, Arf1 is first activated by GBF1 at the cis-Golgi, then by BIG1 and BIG2 at the trans-Golgi and trans-Golgi network (TGN ...
openaire   +2 more sources

The tomato Prf complex is a molecular trap for bacterial effectors based on Pto transphosphorylation [PDF]

, 2013
The bacteria Pseudomonas syringae is a pathogen of many crop species and one of the model pathogens for studying plant and bacterial arms race coevolution.
John P Rathjen, Rathjen, John P, Alexi L. Balmuth, Vardis Ntoukakis, Balmuth, Alexi L, Balmuth, Alexi L., Ra M. E. Jones, Tatiana S Mucyn, Gutierrez, Jose R., Jose R. Gutierrez, Mucyn, Tatiana S, Alexi L. Balmuth, Vardis Ntoukakis (223009), Ntoukakis Vardis, Jose R. Gutierrez (278825), Ntoukakis, Vardis, Alexi L. Balmuth (215165), John P. Rathjen (232061), Jose R Gutierrez, Gutierrez, Jose R, Balmuth Alexi L., Vardis Ntoukakis, Jones, Alexandra M., Tatiana S. Mucyn (278824), Jones, Alexandra M. E, Tatiana S. Mucyn¤a, Rathjen John P., Rathjen, John P., Alexi L Balmuth, Jones Alexandra M. E., Mucyn, Tatiana S., John P. Rathjen*¤b, Alexandra M. E. Jones, Gutierrez Jose R., John P. Rathjen, Alexandra M. E. Jones (50010), Tatiana S. Mucyn, Alexandra M E Jones, Mucyn Tatiana S.   +38 more
core   +2 more sources

EFFECTOR Newsletter Issue No.1 - Feb. 2021

, 2021
EFFECTOR Newsletter Issue No.1 - Feb.
Pantelis KANELLOPOULOS
core   +1 more source

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

Molecular Systems Biology, 2016
Pathogens deliver complex arsenals of translocated effector proteins to host cells during infection, but the extent to which these proteins are regulated once inside the eukaryotic cell remains poorly defined.
Malene L Urbanus, Andrew T Quaile, Peter J Stogios, Mariya Morar, Chitong Rao, Rosa Di Leo, Elena Evdokimova, Mandy Lam, Christina Oatway, Marianne E Cuff, Jerzy Osipiuk, Karolina Michalska, Boguslaw P Nocek, Mikko Taipale, Alexei Savchenko, Alexander W Ensminger   +15 more
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Border Control: Manipulation of the Host–Pathogen Interface by Perihaustorial Oomycete Effectors

Molecular Plant-Microbe Interactions
Filamentous plant pathogens, including fungi and oomycetes, cause some of the most devastating plant diseases. These organisms serve as ideal models for understanding the intricate molecular interplay between plants and the invading pathogens ...
Freddie J. King, Enoch Lok Him Yuen, Tolga O. Bozkurt   +2 more
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice.

, 2009
Chlamydia trachomatis genome is predicted to encode a type III secretion system consisting of more than 40 open reading frames (ORFs). To test whether these ORFs are expressed and immunogenic during chlamydial infection in humans, we expressed 55 ...
Perdue, Sondra, Yeh, I-Tien, Mabey, David, Xiaoyun Zhang, Bailey, Robin, Joel Baseman, Yeh, I.-Tien, Ping Yu, Jie Wang, Martin Holland, Zhang, Yingqian, I.-Tien Yeh, Fan Chen, Zhong, Guangming, Baseman, Joel, Sondra Perdue, Holland, Martin, Lili Chen, Zhang, Xiaoyun, Guangming Zhong, Wang, Jie, Rochelle Shain, Yingqian Zhang, Chen, Fan, David Mabey, Shain, Rochelle, Chen, Lili, Robin Bailey, Yu, Ping   +28 more
core   +1 more source