Results 201 to 210 of about 15,766,464 (312)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Recent advances in dissolving microneedles for breast cancer immunotherapy: local delivery and tumor microenvironment remodeling. [PDF]

Front Immunol
Chen Y, Song L, Zhu Y, Zhang Z, Lu Y, Wang X, Pang H.   +6 more
europepmc   +1 more source

The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function.

Cancer Cell, 2014
R. Johnston, Laetitia Comps-Agrar, J. Hackney, Xin Yu, M. Huseni, Yagai Yang, Summer Park, Vincent Javinal, H. Chiu, B. Irving, D. Eaton, J. Grogan   +11 more
semanticscholar   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Entrance Denied: Deciphering the Transcriptional Circuitry of Wheat Resistance to Zymoseptoria tritici

Molecular Plant-Microbe Interactions
Manish Tiwari
doaj   +1 more source

A strategic approach to managing Immune Effector Cell-Associated Hematotoxicity (ICAHT) during chimeric antigen receptor T-cell therapy. [PDF]

Blood Res
Yoon SE.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Design principles of the cytotoxic CD8⁺ T cell response. [PDF]

Proc Natl Acad Sci U S A
Ukogu OA, Montague Z, Altan-Bonnet G, Nourmohammad A.   +3 more
europepmc   +1 more source

The 3 major types of innate and adaptive cell-mediated effector immunity.

Journal of Allergy and Clinical Immunology, 2015
F. Annunziato, C. Romagnani, S. Romagnani   +2 more
semanticscholar   +1 more source