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Towards population genomics of effector–effector target interactions

New Phytologist, 2010
SummaryPathogen–plant host coevolutionary interactions exert strong natural selection on both organisms, specifically on the genes coding for effectors (pathogens), as well as on those coding for effector targets and R proteins (plant hosts). Natural selection leaves behind DNA sequence signatures on such genes and on linked genomic regions.
Ryohei, Terauchi, Kentaro, Yoshida
openaire   +2 more sources

CD8+ Effector Cells

2004
Publisher Summary The term “effector cell” best describes differentiated T cells with immediate TcR-triggered cytotoxicity or cytokine secretion, as detected in short-term assays, which are currently only feasible in vitro. Investigators agree that antigen recognition by naive CD8+ T cells does not result in either type of effector function (the IL-2
Pierre A, Henkart, Marta, Catalfamo
openaire   +2 more sources

DNA-Damaging Effectors: New Players in the Effector Arena

Trends in Plant Science, 2019
In animal cells, nuclear DNA is the target of genotoxins produced by bacterial pathogens that cause genomic mutations eventually leading to apoptosis, senescence, and carcinogenic development. In response to the insult, the DNA damage response (DDR) is activated to ensure lesion repair.
Camborde, Laurent   +3 more
openaire   +4 more sources

Antibodies as effectors

Veterinary Immunology and Immunopathology, 2002
Antibodies are critical in protection against extracellular microbial pathogens. Although antibodies also play a role in transplant/tumor rejection and in autoimmune disease, this paper focuses on defense against bovine infections. Effector mechanisms of different bovine isotypes, subisotypes and allotypes are discussed.
openaire   +2 more sources

The Genome Biology of Effector Gene Evolution in Filamentous Plant Pathogens.

Annual Review of Phytopathology, 2018
Filamentous pathogens, including fungi and oomycetes, pose major threats to global food security. Crop pathogens cause damage by secreting effectors that manipulate the host to the pathogen's advantage.
A. Sánchez-Vallet   +6 more
semanticscholar   +1 more source

Programmable RNA targeting with the single-protein CRISPR effector Cas7-11

Nature, 2021
Ahsen Özcan   +8 more
semanticscholar   +1 more source

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

Nature Medicine, 2009
S. Nishimura   +12 more
semanticscholar   +1 more source

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