Results 41 to 50 of about 15,766,464 (312)

InnB, a Novel Type III Effector of Bradyrhizobium elkanii USDA61, Controls Symbiosis With Vigna Species

Frontiers in Microbiology, 2018
Bradyrhizobium elkanii USDA61 is incompatible with mung bean (Vigna radiata cv. KPS1) and soybean (Glycine max cv. BARC2) and unable to nodulate either plant.
Hien P. Nguyen, Safirah T. N. Ratu, Michiko Yasuda, Michael Göttfert, Shin Okazaki, Shin Okazaki   +5 more
doaj   +1 more source

Beyond binding: antibody effector functions in infectious diseases

Nature reviews. Immunology, 2017
Antibodies play an essential role in host defence against pathogens by recognizing microorganisms or infected cells. Although preventing pathogen entry is one potential mechanism of protection, antibodies can control and eradicate infections through a ...
Lenette L. Lu, T. Suscovich, S. Fortune, G. Alter   +3 more
semanticscholar   +1 more source

Deciphering the Salmonella T6SS toolkit: two decades of research decoding a versatile bacterial weapon

Journal of Bacteriology
The Type VI Secretion System (T6SS) is a critical fitness and virulence factor of many Gram-negative bacteria. Five T6SS gene clusters have been described in Salmonella, each one encoded within different pathogenicity islands (i.e., SPI-6, SPI-19, SPI-20,
Carlos J. Blondel, Fernando A. Amaya, Felipe Reyes-Méndez, Victoria Soriano-Mora, Carla Vargas, Ayleen Parra, María C. Opazo, Viviana Toledo, María F. Barros-Infante, Carlos A. Santiviago, David Pezoa   +10 more
doaj   +1 more source

Genome and Transcriptome Sequencing Analysis of Fusarium commune Provides Insights into the Pathogenic Mechanisms of the Lotus Rhizome Rot

Microbiology Spectrum, 2022
Fusarium wilt, a vascular wilt caused by F. commune, has been a serious problem for the lotus. Although some F. commune isolate genomes have been sequenced, little is known about the genomic information of the strain that causes Fusarium wilt of aquatic ...
Weigang Kuang, Lianhu Zhang, Lifang Ye, Jian Ma, Xugen Shi, Yachun Lin, Xiaotang Sun, Ruqiang Cui   +7 more
doaj   +1 more source

Gasdermins: Effectors of Pyroptosis [PDF]

Trends in Cell Biology, 2017
Pyroptosis is a form of lytic programmed cell death initiated by inflammasomes, which detect cytosolic contamination or perturbation. This drives activation of caspase-1 or caspase-11/4/5, which cleave gasdermin D, separating its N-terminal pore-forming domain (PFD) from the C-terminal repressor domain (RD).
Miao, Edward A., Kovacs, Stephen B.
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Microbiome manipulation by a soil-borne fungal plant pathogen using effector proteins

Nature Plants, 2020
During colonization of their hosts, pathogens secrete effector proteins to promote disease development through various mechanisms. Increasing evidence shows that the host microbiome plays a crucial role in health, and that hosts actively shape their ...
Nick C. Snelders, Hanna Rovenich, Gabriella C. Petti, M. Rocafort, G. V. D. van den Berg, J. Vorholt, J. Mesters, Michael F. Seidl, R. Nijland, B. Thomma   +9 more
semanticscholar   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

The Molecular Dialogue Between Zymoseptoria tritici and Wheat

Molecular Plant-Microbe Interactions
Zymoseptoria tritici is a highly damaging pathogen that causes high wheat yield losses in temperate climates. Z. tritici emerged during the domestication of wheat in the Fertile Crescent and has been extensively used as a model system for population ...
Lukas Meile, Cristian Carrasco-López, Cécile Lorrain, Gert H. J. Kema, Cyrille Saintenac, Andrea Sánchez-Vallet   +5 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source