Results 41 to 50 of about 747,789 (299)

Effector-Binding-Directed Dimerization and Dynamic Communication between Allosteric Sites of Ribonucleotide Reductase

, 2019
Proteins forming dimers or larger complexes can be strongly influenced by their effector-binding status. We investigated how the effector-binding event is coupled with interface formation via computer simulations, and we quantified the correlation of two
Tongye Shen (203925), Richard J. Lindsay (1649947), Bill Pham (6181139)   +2 more
core   +1 more source

Deciphering the Salmonella T6SS toolkit: two decades of research decoding a versatile bacterial weapon

Journal of Bacteriology
The Type VI Secretion System (T6SS) is a critical fitness and virulence factor of many Gram-negative bacteria. Five T6SS gene clusters have been described in Salmonella, each one encoded within different pathogenicity islands (i.e., SPI-6, SPI-19, SPI-20,
Carlos J. Blondel, Fernando A. Amaya, Felipe Reyes-Méndez, Victoria Soriano-Mora, Carla Vargas, Ayleen Parra, María C. Opazo, Viviana Toledo, María F. Barros-Infante, Carlos A. Santiviago, David Pezoa   +10 more
doaj   +1 more source

Genome and Transcriptome Sequencing Analysis of Fusarium commune Provides Insights into the Pathogenic Mechanisms of the Lotus Rhizome Rot

Microbiology Spectrum, 2022
Fusarium wilt, a vascular wilt caused by F. commune, has been a serious problem for the lotus. Although some F. commune isolate genomes have been sequenced, little is known about the genomic information of the strain that causes Fusarium wilt of aquatic ...
Weigang Kuang, Lianhu Zhang, Lifang Ye, Jian Ma, Xugen Shi, Yachun Lin, Xiaotang Sun, Ruqiang Cui   +7 more
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Hand to mouth: automatic imitation across effector systems [PDF]

, 2007
The effector-specificity of automatic imitation was investigated using a stimulus-response compatibility (SRC) procedure in which participants were required to make an open or a close response with either their hand or their mouth.
Heyes, C., Leighton, J., Jane Leighton, Cecilia Heyes   +3 more
core  

The Irish potato famine pathogen Phytophthora infestans translocates the CRN8 kinase into host plant cells [PDF]

, 2012
Phytopathogenic oomycetes, such as Phytophthora infestans, secrete an arsenal of effector proteins that modulate plant innate immunity to enable infection. We describe CRN8, a host-translocated effector of P. infestans that has kinase activity in planta.
Cakir, Cahid, Tolga O Bozkurt, Sebastian Schornack, Cahid Cakir, Mireille van Damme, Cahid Cakir (142118), Bozkurt, Tolga O, Kamoun, S., Kamoun, Sophien, Jones, A.M.E., Sklenar, Jan, Sophien Kamoun (6132), Cakir, C., Schornack, S., Schornack, Sebastian, van Damme, Mireille, Jan Sklenar (142122), Jones, Alexandra ME, Jones, Alexandra M., Mireille van Damme (142110), Tolga O. Bozkurt (142114), Bozkurt, Tolga O., Sophien Kamoun, Bozkurt, T.O., Sklenar, J., Alexandra M. E. Jones (50010), Alexandra M E Jones, Damme, M., van, Sebastian Schornack (142120), Jan Sklenar   +29 more
core   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

The Molecular Dialogue Between Zymoseptoria tritici and Wheat

Molecular Plant-Microbe Interactions
Zymoseptoria tritici is a highly damaging pathogen that causes high wheat yield losses in temperate climates. Z. tritici emerged during the domestication of wheat in the Fertile Crescent and has been extensively used as a model system for population ...
Lukas Meile, Cristian Carrasco-López, Cécile Lorrain, Gert H. J. Kema, Cyrille Saintenac, Andrea Sánchez-Vallet   +5 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Effector Caspases and Leukemia [PDF]

International Journal of Cell Biology, 2011
Caspases, a family of aspartate-specific cysteine proteases, play a major role in apoptosis and a variety of physiological and pathological processes. Fourteen mammalian caspases have been identified and can be divided into two groups: inflammatory caspases and apoptotic caspases.
Ying Lu, Guo-Qiang Chen
openaire   +3 more sources