Results 31 to 40 of about 15,766,464 (312)
Nucleic Acids Research, 2011 TALENs are important new tools for genome engineering. Fusions of transcription activator-like (TAL) effectors of plant pathogenic Xanthomonas spp. to the FokI nuclease, TALENs bind and cleave DNA in pairs.
T. Čermák +9 more
semanticscholar +1 more source
Apoplastic interactions between plants and plant root intruders
Frontiers in Plant Science, 2015 Numerous pathogenic or parasitic organisms attack plant roots to obtain nutrients, and the apoplast including the plant cell wall is where the plant cell meets such organisms.
Kanako eMitsumasu +2 more
doaj +1 more source
Molecular Plant-Microbe Interactions, 2023 Bipolaris sorokiniana, one of the most devastating hemibiotrophic fungal pathogens, causes root rot, crown rot, leaf blotching, and black embryos of gramineous crops worldwide, posing a serious threat to global food security.
Wanying Zhang +11 more
doaj +1 more source
Transcription factor-based biosensors enlightened by the analyte.
Frontiers in Microbiology, 2015 Whole cell biosensors (WCBs) have multiple applications for environmental monitoring, detecting a wide range of pollutants. WCBs depend critically on the sensitivity and specificity of the transcription factor (TF) used to detect the analyte.
Raul eFernandez-Lopez +3 more
doaj +1 more source
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
Nature, 2010 Innate immunity provides the first line of defence against invading pathogens and provides important cues for the development of adaptive immunity. Type-2 immunity—responsible for protective immune responses to helminth parasites and the underlying cause
D. Neill +11 more
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2016 Brucella abortus, the causative agent of bovine brucellosis, invades and replicates within cells inside a membrane-bound compartment known as the Brucella containing vacuole (BCV). After trafficking along the endocytic and secretory pathways, BCVs mature
Maria Inés Marchesini +4 more
doaj +1 more source
Frontiers in MicrobiologyAs an obligate biotrophic fungus, the leaf rust pathogen Puccinia triticina (Pt) secretes a repertoire of effector proteins into host cells for modulating plant immunity and promoting fungal pathogenesis.
Jianyuan Li +11 more
doaj +1 more source
eLife, 2016 Due to their economic relevance, the study of plant pathogen interactions is of importance. However, elucidating these interactions and their underlying molecular mechanisms remains challenging since both host and pathogen need to be fully genetically ...
Franziska Rabe +24 more
doaj +1 more source
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
Nature, 2013 Somatic mutations in the small GTPase K-Ras are the most common activating lesions found in human cancer, and are generally associated with poor response to standard therapies. Efforts to target this oncogene directly have faced difficulties owing to its
J. Ostrem +4 more
semanticscholar +1 more source
Compendium of human transcription factor effector domains
Molecules and Cells, 2021 Summary Transcription factors (TFs) regulate gene expression by binding to DNA sequences and modulating transcriptional activity through their effector domains.
Luis F. Soto +7 more
semanticscholar +1 more source