Results 261 to 270 of about 407,682 (303)

Towards population genomics of effector–effector target interactions

New Phytologist, 2010
SummaryPathogen–plant host coevolutionary interactions exert strong natural selection on both organisms, specifically on the genes coding for effectors (pathogens), as well as on those coding for effector targets and R proteins (plant hosts). Natural selection leaves behind DNA sequence signatures on such genes and on linked genomic regions.
Ryohei, Terauchi, Kentaro, Yoshida
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Magnaporthe effectors on the move [PDF]

Nature Reviews Microbiology, 2010
A detailed study inPlant Cell has begun to reveal the details of effector secretion and cell-to-cell movement in Magnaporthe oryzae.
exaly   +3 more sources

DNA-Damaging Effectors: New Players in the Effector Arena

Trends in Plant Science, 2019
In animal cells, nuclear DNA is the target of genotoxins produced by bacterial pathogens that cause genomic mutations eventually leading to apoptosis, senescence, and carcinogenic development. In response to the insult, the DNA damage response (DDR) is activated to ensure lesion repair.
Camborde, Laurent, Raynaud, Cécile, Dumas, Bernard, Gaulin, Elodie   +3 more
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Nucleotide effectors of aspartase

Biochemical and Biophysical Research Communications, 1968
Abstract Nucleotide-sensitive preparations of aspartase have been obtained for the first time. With highly purified enzyme fractions, AMP or IMP displays kinetic effects characteristic of an allosteric activator. The kinetic curve shifts from cooperative to Michaelis-Menten, V max is unchanged, and K m decreases.
V R, Williams, R M, Scott
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Assay of enzyme effectors

Talanta, 1987
The effects of various classes of organic compounds and of metal ions on the catalytic activity of horseradish peroxidase in hydrogen peroxide-catalysed o-dianisidine oxidation and, on the activity of alkaline phosphatase in p-nitrophenyl phosphate hydrolysis have been studied.
I F, Dolmanova, T N, Shekhovtsova, V V, Kutcheryaeva   +2 more
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The Macrophage as an Effector Cell

New England Journal of Medicine, 1980
IT has only been a decade since the "mononuclear phagocyte system" was defined, linking monoblasts, promonocytes, monocytes, and the structurally heterogeneous tissue macrophages.
C F, Nathan, H W, Murray, Z A, Cohn
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Signaling and effector pathways

Current Opinion in Rheumatology, 1999
There is increasing evidence that distinct signaling and effector pathways in the rheumatoid synovium result in a cascade of pathophysiologic events. These interactions, which finally lead to progressive joint destruction, are different from all other joint diseases in numerous aspects.
U, Müller-Ladner, R E, Gay, S, Gay
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Immunolocalization of Pathogen Effectors

2011
The use of polyclonal antibodies enables the detection of proteins on a cellular and even subcellular level. Immunolocalization can be used on all pathosystems even if one or both partners of the interaction are unamenable to molecular tools like transformation. This chapter provides detailed information about how to obtain high quality antibodies, how
Eric, Kemen, Kurt, Mendgen, Ralf T, Voegele   +2 more
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Proteins as Biological Effectors

2017
This chapter presented an overview of the role of proteins as biological effectors. From a simplistic point of view, based solely on comparison of the structural diversity of immunoglobulins, blood coagulation proteins, gonadotropins, growth factors, and antiproteins, it could be concluded that the functional mechanisms of these protein families bear ...
M T, Hearn, P G, Stanton, J, Bertolini
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Effector lymphocytes in autoimmunity

Current Opinion in Immunology, 2001
Autoimmune diseases result from complex interactions among different T- and B-lymphocyte subpopulations that target a rapidly growing number of autoantigens on different cell types. The etiology of most spontaneous autoimmune disorders, and both the kinetics and hierarchy of the underlying autoimmune responses are poorly understood.
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