Results 41 to 50 of about 303,721 (255)

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Direct evidence of host-mediated glycosylation of NleA and its dependence on interaction with the COPII complex

Gut Microbes
Non-LEE-encoded Effector A (NleA) is a type III secreted effector protein of enterohaemorrhagic and enteropathogenic Escherichia coli as well as the related mouse pathogen Citrobacter rodentium.
Lindsay Burns, François Le Mauff, Samantha Gruenheid   +2 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Comparative Analysis of Host-Associated Variation in Phytophthora cactorum

Frontiers in Microbiology, 2021
Phytophthora cactorum is often described as a generalist pathogen, with isolates causing disease in a range of plant species. It is the causative agent of two diseases in the cultivated strawberry, crown rot (CR; causing whole plant collapse) and leather
Charlotte F. Nellist, Charlotte F. Nellist, Andrew D. Armitage, Andrew D. Armitage, Helen J. Bates, Helen J. Bates, Maria K. Sobczyk, Maria K. Sobczyk, Matteo Luberti, Laura A. Lewis, Laura A. Lewis, Richard J. Harrison, Richard J. Harrison   +12 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Nuclear processes associated with plant immunity and pathogen susceptibility [PDF]

, 2015
Plants are sessile organisms that have evolved exquisite and sophisticated mechanisms to adapt to their biotic and abiotic environment. Plants deploy receptors and vast signalling networks to detect, transmit and respond to a given biotic threat by ...
Kulagina, Natalja, Huitema, Edgar; id_orcid, Motion, Graham B., Marques Monteiro Amaro, Tiago M.   +3 more
core   +1 more source

Divergent ECC1 effector homologs modulate host-specific virulence in cucurbit-infecting Fusarium oxysporum

Frontiers in Cellular and Infection Microbiology
Fusarium oxysporum (Fo) is a soil-borne fungal pathogen that causes wilt disease in over one hundred plant species, with host-specific strains classified into formae speciales (ff. spp.). For example, Fo f. sp.
Babette V. Vlieger, Like Fokkens, Frank L. W. Takken, Martijn Rep   +3 more
doaj   +1 more source

SUMOylation in Phytopathogen Interactions: Balancing Invasion and Resistance

Frontiers in Cell and Developmental Biology, 2021
Plants are constantly confronted by a multitude of biotic stresses involving a myriad of pathogens. In crops, pathogen infections result in significant agronomical losses worldwide posing a threat to food security.
Manisha Sharma, Manisha Sharma, Diana Fuertes, Jordi Perez-Gil, L. Maria Lois, L. Maria Lois   +5 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Putative T1SS-dependent effectors.

, 2021
Putative T1SS-dependent effectors.
Nguyen-Hung Le (11250765), Mariana G. Sartorio (11250762), Jesus S. Distel (11250759), Nichollas E. Scott (159935), Gisela Di Venanzio (345560), Gabriela Sycz (741267), Wandy L. Beatty (11060349), Mario F. Feldman (159969)   +7 more
core   +1 more source