Results 51 to 60 of about 303,721 (255)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Identification and functional analysis of putative effector proteins from Diaphorina citri and ‘Candidatus Liberibacter asiaticus’

Frontiers in Plant Science
Phloem feeders, such as the psyllid Diaphorina citri (D. citri), feed on plants by inserting their stylet bundle followed by probing the apoplast before reaching the phloem.
Sarmina Dangol, Márcio Fernandes Alves Leite, Mônica Neli Alves, Marc Galland, Paula J. M. van Kleeff, Gertjan Kramer, Josiane C. Darolt, Laudecir L. Raiol-Junior, Laudecir L. Raiol-Junior, Rafael Brandão Garcia, Leandro Peña, Leandro Peña, Nelson Arno Wulff, Marcelo Pedreira de Miranda, Silvio Aparecido Lopes, Harro Bouwmeester, Robert C. Schuurink   +16 more
doaj   +1 more source

The Type III Secretion Effector CteG Mediates Host Cell Lytic Exit of Chlamydia trachomatis

Frontiers in Cellular and Infection Microbiology, 2022
Chlamydia trachomatis is an obligate intracellular bacterium causing ocular and urogenital infections in humans that are a significant burden worldwide. The completion of its characteristic infectious cycle relies on the manipulation of several host cell
Inês Serrano Pereira, Inês Serrano Pereira, Sara Vilela Pais, Vítor Borges, Maria José Borrego, João Paulo Gomes, Luís Jaime Mota, Luís Jaime Mota   +7 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

An Improved Assembly of the Albugo candida Ac2V Genome Reveals the Expansion of the “CCG” Class of Effectors

Molecular Plant-Microbe Interactions, 2022
Albugo candida is an obligate oomycete pathogen that infects many plants in the Brassicaceae family. We resequenced the genome of isolate Ac2V using PacBio long reads and constructed an assembly augmented by Illumina reads.
Oliver J. Furzer, Volkan Cevik, Sebastian Fairhead, Kate Bailey, Amey Redkar, Christian Schudoma, Dan MacLean, Eric B. Holub, Jonathan D. G. Jones   +8 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Yersinia type III secretion : send in the effectors [PDF]

, 2002
Pathogenic Yersinia spp (Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica) have evolved an exquisite method for delivering powerful effectors into cells of the host immune system where they inhibit signaling cascades and block ...
Cornelis, Guy R, Cornelis, Guy, Cornelis, G. R., Guy R. Cornelis, Cornelis GR   +4 more
core   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

How Microbes Twist Jasmonate Signaling around Their Little Fingers

Plants, 2016
Plant immunity relies on a complex network of hormone signaling pathways in which jasmonic acid (JA) plays a central role. Successful microbial pathogens or symbionts have developed strategies to manipulate plant hormone signaling pathways to cause ...
Selena Gimenez-Ibanez, Andrea Chini, Roberto Solano   +2 more
doaj   +1 more source