Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Temporal Decoupling of Biodiversity Effects on Grassland Productivity and Stability. [PDF]
Meng B +5 more
europepmc +1 more source
Ceiling Effect Is Not the Only Effect [PDF]
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
C.-H. Lee, C.-Y. Yu, C.M. Lin, C.W. Liu, H. Lin, W.-H.Chang
Carrier gas effects on the SiGe quantum dots formation
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Integrated Metabolomic and Gut Microbiome Analyses Reveal the Therapeutic Effects of Xuanfei Heji in Rats With Chronic Obstructive Pulmonary Disease. [PDF]
Liu J, Duan N, Xin T, Cao Y, Qian H.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Effect of Different Prophylactic Ankle Taping on Knee Biomechanics During Landing Tasks in Healthy Individuals: A Cross-Sectional Observational Design. [PDF]
Koç M +5 more
europepmc +1 more source

