Results 121 to 130 of about 6,699,838 (364)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Student self-efficacy in college science: an investigation of gender, age, and academic achievement

, 2003
Plan BThis study investigated the relationships between self-efficacy, gender, age, and academic achievement in a two-year college science course, Anatomy and Physiology (A & P). A confidential self-report survey was administered to 216 A & P students to
Witt-Rose, Diane L.
core  

Research on the Mechanism and Material Basis of Corn (Zea mays L.) Waste Regulating Dyslipidemia

Pharmaceuticals
Corn (Zea mays L.) is an essential gramineous food crop. Traditionally, corn wastes have primarily been used in feed, harmless processing, and industrial applications. Except for corn silk, these wastes have had limited medicinal uses. However, in recent
Xiaodong Wang, Lewei Cao, Jiajun Tang, Jiagang Deng, Erwei Hao, Gang Bai, Pei Ling Tang, Jieyi Yang, Huaying Li, Lihao Yao, Cuiwei He, Xiaotao Hou   +11 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Self-efficacy, affectivity and smoking behavior in adolescence [PDF]

, 2011
Background: Research on health-related behaviors confirms the contribution of self-efficacy and affective factors to the initiation and continuation of smoking behavior. The aim was to assess the degree to which affectivity contributes to the association
Geckova, Andrea Madarasova, van Dijk, Jitse P., Geckova, Andrea Madarasova; id_orcid, van Dijk, J.P., Zuzana Veselska, Madarasova-Geckova, A., Veselska, Zuzana, Reijneveld, Sijmen A.; id_orcid, Andrea Madarasova Geckova, Veselska, Z., Jitse P. van Dijk, Reijneveld, S.A., Reijneveld, Sijmen A., Sijmen A. Reijneveld   +13 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Optimisation of the freeze-drying process of Pseudomonas fluorescens strains Pf 153 and CHA0

, 2007
Within the development of a freeze-drying protocol the freezing process and the drying temperature were optimised for the Pseudomonas fluorescens strains Pf 153 and CHA0.
Covi, Johanna, Bisutti, Isabella Linda, Matos da Silva, Ana-Paula, Stephan, Dietrich   +3 more
core  

Efficacy of haemodiafiltration [PDF]

Nephrology Dialysis Transplantation, 2001
V, Wizemann, M, Külz, F, Techert, B, Nederlof   +3 more
openaire   +2 more sources