Results 11 to 20 of about 2,690,939 (252)

Factors contributing to anaemia after uncomplicated falciparum malaria in under five year-old Nigerian children ten years following adoption of artemisinin-based combination therapies as first-line antimalarials

open access: yesBMC Infectious Diseases, 2017
Background Artemisinin-based combination therapies (ACTs) have remained efficacious treatments of acute falciparum malaria in many endemic areas but there is little evaluation of factors contributing to the anaemia of acute falciparum malaria following ...
Akintunde Sowunmi   +21 more
doaj   +1 more source

Effects of Mangifera indica leaves improves blood lipids profile and biochemical indices in high-fat diet-induced hyperlipidaemia rats [PDF]

open access: yesBIO Web of Conferences, 2023
Dyslipidemia a chronic, metabolic syndrome characterized by elevated lipid profiles together with lipid peroxidation in individuals with atherosclerotic cardiovascular disease (CVD).
Liu Lijia   +3 more
doaj   +1 more source

Immune Activity of Polysaccharide Fractions Isolated from Korean Red Ginseng

open access: yesMolecules, 2020
Korean red ginseng (KRG)’s pharmacological efficacy and popular immunomodulatory effects have already been proven in many studies; however, the component of KRG that is effective in immune activity has not been studied before.
Soo Hyun Youn   +5 more
doaj   +1 more source

Diesel Exhaust Particulates Enhances Susceptibility of LPS-Induced Acute Lung Injury through Upregulation of the IL-17 Cytokine-Derived TGF-β1/Collagen I Expression and Activation of NLRP3 Inflammasome Signaling in Mice

open access: yesBiomolecules, 2021
Diesel exhaust particulates (DEP) adversely affect the respiratory system and exacerbate lung diseases, resulting in high mortality rates. However, its pathogenesis is complicated, and the mechanisms involved are incompletely understood.
Dong Im Kim, Mi-Kyung Song, Kyuhong Lee
doaj   +1 more source

miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma

open access: yesFrontiers in Oncology, 2021
MicroRNAs are a group of endogenous small non-coding RNAs commonly dysregulated in tumorigenesis, including glioblastoma (GBM), the most malignant brain tumor with rapid proliferation, diffuse invasion, and therapeutic resistance.
Hongkun Qin   +8 more
doaj   +1 more source

Declining responsiveness of childhood Plasmodium falciparum infections to artemisinin-based combination treatments ten years following deployment as first-line antimalarials in Nigeria

open access: yesInfectious Diseases of Poverty, 2019
Background The development and spread of artemisinin-resistant Plasmodium falciparum malaria in Greater Mekong Subregion has created impetus for continuing global monitoring of efficacy of artemisinin-based combination therapies (ACTs).
Akintunde Sowunmi   +35 more
doaj   +1 more source

Coaching Efficacy: The Leadership Efficacy Model [PDF]

open access: yes, 2020
This chapter introduces the leadership efficacy model applied to sports coaching. It is proposed in the model that leadership efficacy depends on the congruence between the conceptual cycle of leadership and the practical cycle of leadership and also by considering the leadership styles assumed by coaches and the moderating influence of the antecedent ...
openaire   +2 more sources

Immuno-enhancement effects of Korean Red Ginseng in healthy adults: a randomized, double-blind, placebo-controlled trial

open access: yesJournal of Ginseng Research, 2021
Background: Most clinical studies of immune responses activated by Korean Red Ginseng (KRG) have been conducted exclusively in patients. However, there is still a lack of clinical research on immune-boosting benefits of KRG for healthy persons.
Sun Hee Hyun   +7 more
doaj   +1 more source

Anti-Osteoporotic Effect of Viscozyme-Assisted Polysaccharide Extracts from Portulaca oleracea L. on H2O2-Treated MC3T3-E1 Cells and Zebrafish

open access: yesSeparations, 2022
This study aims to screen and characterize the protective effect of polysaccharides from Portulaca oleracea L. (POP) against H2O2-stimulated osteoblast apoptosis in vivo and in vitro.
Yunhua Fu   +8 more
doaj   +1 more source

Bone marrow mesenchymal stem cell-derived exosomal microRNA regulates microglial polarization [PDF]

open access: yesPeerJ, 2023
Objective This study aimed to explore the effects of bone marrow mesenchymal stem cell (BMSC)-derived exosomal miR-146a-5p on microglial polarization and the potential underlying mechanisms in oxygen-glucose deprivation (OGD)-exposed microglial cells ...
Xianwei Huang   +5 more
doaj   +2 more sources

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