Results 11 to 20 of about 8,924,877 (409)

Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19

New England Journal of Medicine, 2021
Background The Ad26.COV2.S vaccine is a recombinant, replication-incompetent human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein in a prefusion-stabilized conformation.
J. Sadoff, G. Gray, A. Vandebosch, V. Cárdenas, Georgi Shukarev, B. Grinsztejn, P. Goepfert, C. Truyers, H. Fennema, B. Spiessens, K. Offergeld, Gert Scheper, K. Taylor, M. Robb, J. Treanor, D. Barouch, J. Stoddard, M. Ryser, M. Marovich, K. Neuzil, L. Corey, N. Cauwenberghs, T. Tanner, K. Hardt, Javier Ruiz-Guiñazú, Mathieu le Gars, H. Schuitemaker, J. van Hoof, F. Struyf, M. Douoguih   +29 more
semanticscholar   +1 more source

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

New England Journal of Medicine, 2020
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the resulting coronavirus disease 2019 (Covid-19) have afflicted tens of millions of people in a worldwide pandemic.
F. Polack, Stephen J. Thomas, N. Kitchin, J. Absalon, A. Gurtman, S. Lockhart, John L. Perez, Gonzalo Pérez Marc, E. Moreira, C. Zerbini, R. Bailey, K. Swanson, Satrajit Roychoudhury, K. Koury, Ping Li, W. Kalina, David Cooper, R. Frenck, L. Hammitt, Ö. Türeci, H. Nell, A. Schaefer, S. Ünal, D. Tresnan, Susan H. Mather, P. Dormitzer, U. Şahin, K. Jansen, W. Gruber   +28 more
semanticscholar   +1 more source

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

New England Journal of Medicine, 2020
Background Vaccines are needed to prevent coronavirus disease 2019 (Covid-19) and to protect persons who are at high risk for complications. The mRNA-1273 vaccine is a lipid nanoparticle–encapsulated mRNA-based vaccine that encodes the prefusion ...
L. Baden, Hana M. El Sahly, B. Essink, K. Kotloff, S. Frey, R. Novak, D. Diemert, S. Spector, N. Rouphael, C. Creech, J. Mcgettigan, Shishir Kehtan, N. Segall, Joel Solis, A. Brosz, C. Fierro, H. Schwartz, K. Neuzil, L. Corey, P. Gilbert, H. Janes, D. Follmann, M. Marovich, J. Mascola, L. Polakowski, J. Ledgerwood, B. Graham, H. Bennett, R. Pajon, C. Knightly, B. Leav, W. Deng, Honghong Zhou, Shu Han, M. Ivarsson, Jacqueline M. Miller, T. Zaks   +36 more
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Roots and stems of Kadsura coccinea extract induced developmental toxicity in zebrafish embryos/larvae through apoptosis and oxidative stress

Pharmaceutical Biology, 2020
Context Although the roots and stems of Kadsura coccinea (Lem.) A. C. Smith. [Schisandraceae] are herbs and traditional foods in Li nationality, its toxicity remains unclear. Objective To study developmental toxicity of K.
Zhongshang Xia, Erwei Hao, Zhangmei Chen, Mingzhe Zhang, Yanting Wei, Man Wei, Xiaotao Hou, Zhengcai Du, Jiagang Deng   +8 more
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Physiological and pharmacological features of the non-saponin components in Korean Red Ginseng

Journal of Ginseng Research, 2020
Panax ginseng, a medicinal plant, has been used as a blood-nourishing tonic for thousands of years in Asia, including Korea and China. P. ginseng exhibits adaptogen activity that maintains homeostasis by restoring general biological functions and non ...
Sun Hee Hyun, Sung Won Kim, Hwi Won Seo, Soo Hyun Youn, Jong Soo Kyung, Yong Yook Lee, Gyo In, Chae-Kyu Park, Chang-Kyun Han   +8 more
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Gnetum montanum extract induces apoptosis by inhibiting the activation of AKT in SW480 human colon cancer cells

Pharmaceutical Biology, 2022
Context Gnetum montanum Markgr. (Gnetaceae) is used to treat rheumatic arthralgia and bruises in the clinic.Objective To exam the activity and mechanism of G.
Xianglong Pan, Xiaotao Hou, Fan Zhang, Peiling Tang, Wanruo Wan, Zixia Su, Yeguo Yang, Wei Wei, Zhengcai Du, Jiagang Deng, Erwei Hao   +10 more
doaj   +1 more source

Respiratory virus shedding in exhaled breath and efficacy of face masks

Nature Network Boston, 2020
We identified seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory illness.
Nancy H. L. Leung, D. Chu, E. Shiu, Kwok-Hung Chan, J. Mcdevitt, Benien J. P. Hau, H. Yen, Yuguo Li, D. Ip, J. Peiris, W. Seto, G. Leung, D. Milton, B. Cowling   +13 more
semanticscholar   +1 more source

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine through 6 Months

New England Journal of Medicine, 2021
Background BNT162b2 is a lipid nanoparticle–formulated, nucleoside-modified RNA vaccine encoding a prefusion-stabilized, membrane-anchored severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) full-length spike protein.
Stephen J. Thomas, E. Moreira, N. Kitchin, J. Absalon, A. Gurtman, S. Lockhart, John L. Perez, Gonzalo Pérez Marc, F. Polack, C. Zerbini, R. Bailey, K. Swanson, Xia Xu, Satrajit Roychoudhury, K. Koury, S. Bouguermouh, W. Kalina, David Cooper, R. Frenck, L. Hammitt, Ö. Türeci, H. Nell, A. Schaefer, S. Ünal, Qi Yang, P. Liberator, D. Tresnan, Susan H. Mather, P. Dormitzer, U. Şahin, W. Gruber, K. Jansen   +31 more
semanticscholar   +1 more source

Factors contributing to anaemia after uncomplicated falciparum malaria in under five year-old Nigerian children ten years following adoption of artemisinin-based combination therapies as first-line antimalarials

BMC Infectious Diseases, 2017
Background Artemisinin-based combination therapies (ACTs) have remained efficacious treatments of acute falciparum malaria in many endemic areas but there is little evaluation of factors contributing to the anaemia of acute falciparum malaria following ...
Akintunde Sowunmi, Bayo Fatunmbi, Kazeem Akano, Olubunmi A. Wewe, Chimere Agomo, Finomo Finomo, Joy Ebenebe, Nma Jiya, Jose Ambe, Robinson Wammanda, Godwin Ntadom, Olugbenga Mokuolu, George Emechebe, Nnenna Ezeigwe, Adejumoke I. Ayede, Elsie O. Adewoye, Grace O. Gbotosho, Onikepe A. Folarin, Christian T. Happi, Stephen Oguche, Wellington A. Oyibo, Francis Useh   +21 more
doaj   +1 more source

Comparative study to evaluate the wound healing efficacy of topical formulations containing Triticum aestivum L. (Triticum vulgare) in a native human skin model [PDF]

Surgical & Cosmetic Dermatology, 2022
Introduction: Plant extracts and actives derived from plants were developed to improve and enhance the skin healing process including Triticum aestivum L. (Triticum vulgare).
Brayan Styven Merchan Rojas, Jose Luis De-la-hoz, Gustavo Facchini, Gustavo Henrique da Silva, Ana Lúcia Tabarini Alves Pinheiro, Samara Eberlin   +5 more
doaj   +1 more source